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- W2178508613 abstract "Changes in respiratory mechanics and single-breath diffusing capacity for carbon monoxide were compared in cats during exposure to low concentrations of ozone (1.0, 0.5, and 0.26 ppm). The animals were anesthetized, paralyzed, and mechanically ventilated through a tracheal cannula with a respiratory pump; exposure lasted an average of 4.6 hours. Pulmonary flow resistance, dynamic compliance, slow volume-pressure curves, vital capacity, and functional residual capacity were measured. Pulmonary resistance increased in almost all of the animals exposed to 1.0 and 0.5 ppm; only 2 of the cats exposed to 0.26 ppm showed an increase in pulmonary resistance. Atropine produced only a partial reversal of the increase in pulmonary resistance. Changes in dynamic compliance at 25 breaths per minute and diffusing capacity for carbon monoxide were less frequent and less marked than the change in pulmonary resistance. Vital capacity did not change; alveolar stability appeared to be unaffected, as evidenced by the shape o..." @default.
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- W2178508613 date "2015-05-14" @default.
- W2178508613 modified "2023-09-24" @default.
- W2178508613 title "Acute Effects of Ozone on Lungs of Cats" @default.
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