FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2178701859> ?p ?o ?g. }

• W2178701859 endingPage "406" @default.
• W2178701859 startingPage "406" @default.
• W2178701859 abstract "The photodynamic properties of meta-tetra(hydroxyphenyl)chlorin (mTHPC), a promising second-generation photosensitizer, were investigated using a human colon adenocarcinoma cell line (Colo 201 cells). The study on photocytotoxicity using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide reduction assay showed that mTHPC was an effective photosensitizer on Colo 201 cells. The photocytotoxicity of mTHPC showed both drug and light dose-dependent characteristics. To reach LD50, namely, the dose at which 50% of the cells were killed, only 0.45+/-0.15 microg/mL of mTHPC and 3 J/cm2 of light dose were required. The presence of 10% fetal calf serum in culture medium significantly decreased the incorporation of mTHPC into cells and resulted in the reduction of photodynamic efficacy. Using confocal laser scanning microscopy, mTHPC was first shown to localize in lysosomes rather than in mitochondria. Furthermore, nuclear stainings demonstrated that photodynamic therapy with mTHPC induced apoptosis in Colo 201 cells." @default.
• W2178701859 created "2016-06-24" @default.
• W2178701859 creator A5021520521 @default.
• W2178701859 creator A5048269616 @default.
• W2178701859 creator A5057665558 @default.
• W2178701859 creator A5088642717 @default.
• W2178701859 date "2002-01-01" @default.
• W2178701859 modified "2023-10-15" @default.
• W2178701859 title "Photodynamic Effects of mTHPC on Human Colon Adenocarcinoma Cells: Photocytotoxicity, Subcellular Localization and Apoptosis¶" @default.
• W2178701859 cites W1534026537 @default.
• W2178701859 cites W1877053426 @default.
• W2178701859 cites W1975703730 @default.
• W2178701859 cites W1981095027 @default.
• W2178701859 cites W1990427071 @default.
• W2178701859 cites W1997857002 @default.
• W2178701859 cites W1998424046 @default.
• W2178701859 cites W1998887606 @default.
• W2178701859 cites W2004814007 @default.
• W2178701859 cites W2017657441 @default.
• W2178701859 cites W2029130214 @default.
• W2178701859 cites W2034564919 @default.
• W2178701859 cites W2037621047 @default.
• W2178701859 cites W2040775167 @default.
• W2178701859 cites W2044096564 @default.
• W2178701859 cites W2057909925 @default.
• W2178701859 cites W2059851577 @default.
• W2178701859 cites W2065226357 @default.
• W2178701859 cites W2078121389 @default.
• W2178701859 cites W2078297328 @default.
• W2178701859 cites W2084343059 @default.
• W2178701859 cites W2091210609 @default.
• W2178701859 cites W2117462949 @default.
• W2178701859 cites W2141086199 @default.
• W2178701859 cites W2142859236 @default.
• W2178701859 cites W2151826696 @default.
• W2178701859 cites W2157222301 @default.
• W2178701859 cites W2164416785 @default.
• W2178701859 cites W2165021798 @default.
• W2178701859 cites W2330013684 @default.
• W2178701859 cites W2331511506 @default.
• W2178701859 cites W2742512161 @default.
• W2178701859 cites W4211024586 @default.
• W2178701859 cites W4253258573 @default.
• W2178701859 cites W4301481911 @default.
• W2178701859 doi "https://doi.org/10.1562/0031-8655(2002)075<0406:peomoh>2.0.co;2" @default.
• W2178701859 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12003131" @default.
• W2178701859 hasPublicationYear "2002" @default.
• W2178701859 type Work @default.
• W2178701859 sameAs 2178701859 @default.
• W2178701859 citedByCount "48" @default.
• W2178701859 countsByYear W21787018592012 @default.
• W2178701859 countsByYear W21787018592013 @default.
• W2178701859 countsByYear W21787018592014 @default.
• W2178701859 countsByYear W21787018592015 @default.
• W2178701859 countsByYear W21787018592016 @default.
• W2178701859 countsByYear W21787018592017 @default.
• W2178701859 countsByYear W21787018592019 @default.
• W2178701859 countsByYear W21787018592021 @default.
• W2178701859 countsByYear W21787018592022 @default.
• W2178701859 countsByYear W21787018592023 @default.
• W2178701859 crossrefType "journal-article" @default.
• W2178701859 hasAuthorship W2178701859A5021520521 @default.
• W2178701859 hasAuthorship W2178701859A5048269616 @default.
• W2178701859 hasAuthorship W2178701859A5057665558 @default.
• W2178701859 hasAuthorship W2178701859A5088642717 @default.
• W2178701859 hasConcept C12554922 @default.
• W2178701859 hasConcept C153911025 @default.
• W2178701859 hasConcept C178790620 @default.
• W2178701859 hasConcept C185592680 @default.
• W2178701859 hasConcept C190283241 @default.
• W2178701859 hasConcept C202751555 @default.
• W2178701859 hasConcept C20639190 @default.
• W2178701859 hasConcept C2778178086 @default.
• W2178701859 hasConcept C2781323092 @default.
• W2178701859 hasConcept C2781469039 @default.
• W2178701859 hasConcept C28859421 @default.
• W2178701859 hasConcept C502942594 @default.
• W2178701859 hasConcept C54355233 @default.
• W2178701859 hasConcept C55493867 @default.
• W2178701859 hasConcept C75473681 @default.
• W2178701859 hasConcept C81885089 @default.
• W2178701859 hasConcept C86803240 @default.
• W2178701859 hasConceptScore W2178701859C12554922 @default.
• W2178701859 hasConceptScore W2178701859C153911025 @default.
• W2178701859 hasConceptScore W2178701859C178790620 @default.
• W2178701859 hasConceptScore W2178701859C185592680 @default.
• W2178701859 hasConceptScore W2178701859C190283241 @default.
• W2178701859 hasConceptScore W2178701859C202751555 @default.
• W2178701859 hasConceptScore W2178701859C20639190 @default.
• W2178701859 hasConceptScore W2178701859C2778178086 @default.
• W2178701859 hasConceptScore W2178701859C2781323092 @default.
• W2178701859 hasConceptScore W2178701859C2781469039 @default.
• W2178701859 hasConceptScore W2178701859C28859421 @default.
• W2178701859 hasConceptScore W2178701859C502942594 @default.
• W2178701859 hasConceptScore W2178701859C54355233 @default.
• W2178701859 hasConceptScore W2178701859C55493867 @default.
• W2178701859 hasConceptScore W2178701859C75473681 @default.
• W2178701859 hasConceptScore W2178701859C81885089 @default.

• next