FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2178713876> ?p ?o ?g. }

• W2178713876 endingPage "150" @default.
• W2178713876 startingPage "139" @default.
• W2178713876 abstract "Emergence agitation (EA) is an adverse effect after sevoflurane anesthesia in pediatric patients. The effectiveness of prophylactic μ-opioid agonists fentanyl, remifentanil, sufentanil, and alfentanil in preventing EA is debatable.A literature search was conducted to identify clinical trials that observed the effect of μ-opioid agonists fentanyl, remifentanil, sufentanil, and alfentanil on preventing EA in pediatric patients under sevoflurane anesthesia. The statistical software RevMan 5.3 was used for meta-analysis. Data from each study were combined using the relative ratio (RR), weighted mean differences, and their associated 95% confidence intervals. I(2) was used to evaluate heterogeneity. Subgroup analysis was conducted to investigate the possible influences of patient age, adenotonsillectomy, premedication, N2 O, propofol, and regional block/local anesthetics on preventing EA with prophylactic administration of μ-opioid agonists. Publication bias was checked using funnel plots and Begg's test.This meta-analysis showed the inclusion of 19 randomized controlled trials with 1528 patients (857 patients received μ-opioid agonists therapy and 671 patients had placebo). The pooled data indicated that prophylactic μ-opioid agonists fentanyl, remifentanil, sufentanil, and alfentanil significantly decreased the incidence of EA [RR = 0.49 (0.38, 0.64), I(2) = 42%, P = 0.04; RR = 0.57 (0.33, 0.99), I(2) = 37%, P = 0.19; RR = 0.18 (0.08, 0.39), I(2) = 0%, P = 0.98; and RR = 0.56 (0.40, 0.78), I(2) = 6%, P = 0.34, respectively]. All subgroup analyses strengthened the proof for lower incidence of EA under sevoflurane anesthesia after fentanyl administration. A possibility of publication bias was detected in the fentanyl group.This meta-analysis suggested that prophylactic μ-opioid agonists fentanyl, remifentanil, sufentanil, and alfentanil could significantly decrease the incidence of EA under sevoflurane anesthesia in children compared to placebo. Considering the limitations of the included studies, more clinical studies are required." @default.
• W2178713876 created "2016-06-24" @default.
• W2178713876 creator A5022928293 @default.
• W2178713876 creator A5030766348 @default.
• W2178713876 creator A5039401814 @default.
• W2178713876 creator A5041744189 @default.
• W2178713876 creator A5075203372 @default.
• W2178713876 creator A5087752080 @default.
• W2178713876 date "2015-11-28" @default.
• W2178713876 modified "2023-10-16" @default.
• W2178713876 title "μ-Opioid agonists for preventing emergence agitation under sevoflurane anesthesia in children: a meta-analysis of randomized controlled trials" @default.
• W2178713876 cites W105498287 @default.
• W2178713876 cites W112427433 @default.
• W2178713876 cites W1497082223 @default.
• W2178713876 cites W1508293915 @default.
• W2178713876 cites W1554040650 @default.
• W2178713876 cites W1596750399 @default.
• W2178713876 cites W1852246421 @default.
• W2178713876 cites W1968298691 @default.
• W2178713876 cites W1973854659 @default.
• W2178713876 cites W1997149740 @default.
• W2178713876 cites W2002593693 @default.
• W2178713876 cites W2005303049 @default.
• W2178713876 cites W2007595870 @default.
• W2178713876 cites W2009235634 @default.
• W2178713876 cites W2011694298 @default.
• W2178713876 cites W2012932483 @default.
• W2178713876 cites W2018346981 @default.
• W2178713876 cites W2019473536 @default.
• W2178713876 cites W2020898025 @default.
• W2178713876 cites W2021287233 @default.
• W2178713876 cites W2024549267 @default.
• W2178713876 cites W2029166714 @default.
• W2178713876 cites W2031941946 @default.
• W2178713876 cites W2032366861 @default.
• W2178713876 cites W2038505504 @default.
• W2178713876 cites W2042843181 @default.
• W2178713876 cites W2045053402 @default.
• W2178713876 cites W2050434119 @default.
• W2178713876 cites W2057694293 @default.
• W2178713876 cites W2066885240 @default.
• W2178713876 cites W2072713328 @default.
• W2178713876 cites W2075724868 @default.
• W2178713876 cites W2090017566 @default.
• W2178713876 cites W2093705530 @default.
• W2178713876 cites W2093948267 @default.
• W2178713876 cites W2098923148 @default.
• W2178713876 cites W2100780988 @default.
• W2178713876 cites W2103270412 @default.
• W2178713876 cites W2117524167 @default.
• W2178713876 cites W2137977555 @default.
• W2178713876 cites W2155966644 @default.
• W2178713876 cites W2156620125 @default.
• W2178713876 cites W2168003395 @default.
• W2178713876 cites W2185261556 @default.
• W2178713876 cites W2321329736 @default.
• W2178713876 cites W4245022632 @default.
• W2178713876 cites W4255105016 @default.
• W2178713876 doi "https://doi.org/10.1111/pan.12815" @default.
• W2178713876 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26614352" @default.
• W2178713876 hasPublicationYear "2015" @default.
• W2178713876 type Work @default.
• W2178713876 sameAs 2178713876 @default.
• W2178713876 citedByCount "22" @default.
• W2178713876 countsByYear W21787138762017 @default.
• W2178713876 countsByYear W21787138762018 @default.
• W2178713876 countsByYear W21787138762019 @default.
• W2178713876 countsByYear W21787138762020 @default.
• W2178713876 countsByYear W21787138762021 @default.
• W2178713876 countsByYear W21787138762022 @default.
• W2178713876 countsByYear W21787138762023 @default.
• W2178713876 crossrefType "journal-article" @default.
• W2178713876 hasAuthorship W2178713876A5022928293 @default.
• W2178713876 hasAuthorship W2178713876A5030766348 @default.
• W2178713876 hasAuthorship W2178713876A5039401814 @default.
• W2178713876 hasAuthorship W2178713876A5041744189 @default.
• W2178713876 hasAuthorship W2178713876A5075203372 @default.
• W2178713876 hasAuthorship W2178713876A5087752080 @default.
• W2178713876 hasConcept C126322002 @default.
• W2178713876 hasConcept C141071460 @default.
• W2178713876 hasConcept C168563851 @default.
• W2178713876 hasConcept C170493617 @default.
• W2178713876 hasConcept C187960798 @default.
• W2178713876 hasConcept C197934379 @default.
• W2178713876 hasConcept C2776277131 @default.
• W2178713876 hasConcept C2777019824 @default.
• W2178713876 hasConcept C2778300832 @default.
• W2178713876 hasConcept C2778891214 @default.
• W2178713876 hasConcept C2781063702 @default.
• W2178713876 hasConcept C2781072394 @default.
• W2178713876 hasConcept C2781091344 @default.
• W2178713876 hasConcept C2781453256 @default.
• W2178713876 hasConcept C42219234 @default.
• W2178713876 hasConcept C44249647 @default.
• W2178713876 hasConcept C71924100 @default.
• W2178713876 hasConcept C82789193 @default.
• W2178713876 hasConceptScore W2178713876C126322002 @default.
• W2178713876 hasConceptScore W2178713876C141071460 @default.

• next