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- W2178720044 abstract "We thank Drs De Santo and Esquinas for their commentary on our article “Sleep apnea is associated with new-onset atrial fibrillation after coronary artery bypass grafting” [1]. It is encouraging to see the common ground that sleep apnea is a prevalent condition and it is an important predictorof post–coronary artery bypassgrafting (CABG) atrial fibrillation (AF). Further studies to evaluate the role of continuous positive airways pressure in reducing the burden of post-CABG AF are warranted. We acknowledge the methodological limitations raised by Drs De Santo and Esquinas. Yet, it is important to highlight that before our study, there was only 1 similar study (published 20 years ago) that used sleep study to diagnosed sleep apnea [2] .A ll the subsequent studies that evaluated the relationship between sleep apnea and post-CABG AF had used a less accurate method of screening questionnaires to diagnose sleep apnea [3-5]. Compared with the aforementioned studies, our studies incorporated most comprehensive data such as angiographic and echocardiographic data. Considering the relatively small sample size and hence limited study power, introducing too many variables would have predisposed the study to type 2 error. Moreover, using clinical history and 12-lead electrocardiography to exclude known AF is an acceptable practice in clinical research. By excluding clinically overt AF, the residual effect of silent AF on our study, if any, should be negligible. Besides, our study was designed to specifically evaluate the role of sleep apnea on occurrence of post-CABG AF; other independent predictorssuch asleftatrialdiameter were not discussedin details.Finally, occurrence of AF before hospital discharge was the end point defined a prior by our study team. We are conducting extended follow-up on the recruited patients to detect incidence of AF recurrence." @default.
- W2178720044 created "2016-06-24" @default.
- W2178720044 creator A5076880854 @default.
- W2178720044 date "2016-02-01" @default.
- W2178720044 modified "2023-10-17" @default.
- W2178720044 title "Reply to “How delineate OSA and CPAP link in postoperative atrial fibrillation conundrum?”" @default.
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- W2178720044 doi "https://doi.org/10.1016/j.jcrc.2015.10.006" @default.
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