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- W2178735163 abstract "Substitution of 7-OH by small hydrophobic groups on zanamivir resulted in the retaining of low nanomolar inhibitory activities against not only influenza A virus sialidase but also influenza A virus in cell culture. These compounds were prepared by treatment of the corresponding 7-substituted sialic acids derived from 4-modified N-acetyl-D-mannosamine (ManNAc) using enzyme-catalyzed aldol condensation." @default.
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- W2178735163 date "2002-08-01" @default.
- W2178735163 modified "2023-09-23" @default.
- W2178735163 title "Synthesis and anti-influenza virus activity of 4-guanidino-7-substituted Neu5Ac2en derivatives" @default.
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- W2178735163 doi "https://doi.org/10.1016/s0960-894x(02)00328-1" @default.
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