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• W2178821992 abstract "The safety of elective hand surgery in women previously treated for same-sided breast cancer is controversial due to concerns of developing late onset upper extremity lymphedema. We hypothesized that the prevalence of lymphedema following elective hand surgery among breast cancer survivors would be low but may be more likely depending on the type of axillary dissection and adjuvant treatment received. A retrospective cohort of breast cancer patients treated with axillary lymph node dissection (ALND), sentinel lymph node biopsy (SLNB) and/or radiation therapy (RT) was identified between 1997-2012. Patients with ipsilateral elective hand surgery following their breast cancer treatment were included if there was at least 1 year of follow up and no history lymphedema following breast cancer treatment. The primary outcome was documented lymphedema following hand surgery. Demographic data and clinical information pertaining to both hand surgery and breast cancer treatment and were compared between patients with and without lymphedema. Dichotomous and continuous variables were compared with Fisher’s exact and Student T-tests, respectively. The analysis included 103 patients, of which four (3.8%) had documented lymphedema following hand surgery, which developed early and was self-limited. Patient with and without lymphedema were similar in age, hand surgery procedure, and tourniquet use. Average tourniquet time was greater among women without lymphedema (23 vs. 9 minutes, P =0.02). All patients (4/4) with late-onset lymphedema received adjuvant chemotherapy (vs. 29% in non-lymphedema group, P = .009) and RT with either ALND or SLNB (vs 41% of patients without lymphedema, P = .01). Radiotherapy or any type of axillary dissection alone was not associated with lymphedema following elective hand surgery. Lymphedema was associated with a shorter interval between hand surgery and completion of breast cancer surgery (2.1 vs. 6.2 years, P < .01) and RT (2.0 vs. 3.3 years, P = .051). •Lymphedema is uncommon and self-limited following elective hand surgery among breast cancer survivors.•A combination of RT and ALND or SLNB and a shorter interval between hand surgery and breast cancer treatments (ALND/SLNB and RT) appears to put these women at higher risk of developing late onset lymphedema after elective hand surgery.•Tourniquet use appears to be safe for elective hand surgery among this patient population." @default.
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• W2178821992 date "2015-09-01" @default.
• W2178821992 modified "2023-09-25" @default.
• W2178821992 title "Late Onset Upper Extremity Lymphedema Following Elective Hand Surgery in Breast Cancer Survivors" @default.
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• W2178821992 doi "https://doi.org/10.1016/j.jhsa.2015.06.014" @default.
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