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- W2179662979 abstract "Macromolecules are known to precipitate selectively in concentrated solutions of polyethylene glycol. This report describes the use of polyethylene glycol 6000 to distinguish macroamylase from normal-sized serum amylase. Preliminary studies indicated that a PEG concentration of 12% and a 10-min incubation at 37 degrees C separated normal serum amylase from macroamylase. Using these conditions, study of 18 macroamylase-containing sera showed precipitation of at least 73% of the amylase activity. In contrast, in 46 normal sera and 16 hyperamylasemic (but not macroamylasemic) sera, less than 52% of the amylase activity was precipitated by polyethylene glycol. This test provides a rapid, simple, and accurate means of determining if macroamylasemia is the cause of hyperamylasemia." @default.
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- W2179662979 date "1982-08-01" @default.
- W2179662979 modified "2023-10-12" @default.
- W2179662979 title "A Rapid and Simple Assay to Determine if Macroamylase Is the Cause of Hyperamylasemia" @default.
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- W2179662979 doi "https://doi.org/10.1016/s0016-5085(82)80331-4" @default.
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