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- W2179671639 abstract "A useful approach for the synthesis of pharmacologically active tetrahydropyridinylbenzimidazoles is described. 2-Pyridin-3-ylbenzimidazoles 3a-d have been synthesized by condensation of 3-pyridinecarbox-aldehyde 1 with substituted 1,2-phenylenediamines 2a-d following oxidative cyclization with iodobenzene diacetate. Methylation of 3a-d with iodomethane and potassium hydroxide, subsequent formation of methylpyridinium salts 4a-d and 7a-d and reduction thereafter afforded tetrahydropyridinylbenzimidazoles 5a-d and 8a-d." @default.
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- W2179671639 date "2003-01-01" @default.
- W2179671639 modified "2023-09-27" @default.
- W2179671639 title "Synthesis of 2-(1-methyl-1,2,5,6-tetrahydropyridin-3-yl)benzimidazoles" @default.
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- W2179671639 doi "https://doi.org/10.1002/jhet.5570400104" @default.
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