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• W2179699086 abstract "<h3>Objective</h3> To propose the Schwalbe line (SL) as a new anatomical landmark, independent of the scleral spur (SS) location, for assessing anterior chamber angle (ACA) width quantitatively with high-definition optical coherence tomography (HD-OCT). <h3>Methods</h3> Study subjects underwent dark-room gonioscopy and HD-OCT in one randomly selected eye. The authors developed a computer-aided program to define two new quantitative parameters for assessing ACA width: Schwalbe line-angle opening distance (SL-AOD) measured at the SL, and Schwalbe line-trabecular–iris space area (SL-TISA) measured 500 μm from the SL. The associations between SL parameters, SS parameters and gonioscopic grading were evaluated. <h3>Results</h3> Seventy-three (47 females, 26 males) subjects were recruited, the majority of whom were Chinese (89%). The authors excluded 29 images (19.9%) owing to poor image quality, leaving 117 HD-OCT images (65 nasal, 52 temporal) for analysis. SL and SS could be identified in 95% and 85% of quadrants respectively (p=0.035). SL-AOD and SL-TISA were significantly correlated with SS parameters (all r≥0.85) and gonioscopic grading (all r≥0.69). In eyes with closed angles (n=36), SL parameters showed strong correlations with gonioscopic grading (r ranged from 0.43 to 0.44). <h3>Conclusions</h3> Novel angle parameters, based on SL as a landmark, may be useful to quantify ACA width and to assess for risk of angle closure." @default.
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• W2179699086 date "2015-10-28" @default.
• W2179699086 modified "2023-10-18" @default.
• W2179699086 title "Efficacy of nonvenous medications for acute convulsive seizures" @default.
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• W2179699086 doi "https://doi.org/10.1212/wnl.0000000000002142" @default.
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