FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2179755779> ?p ?o ?g. }

• W2179755779 endingPage "1053" @default.
• W2179755779 startingPage "1050" @default.
• W2179755779 abstract "Male infertility contributes to a substantial share to couple infertility. Despite scientific efforts, most cases of male infertility remain 'idiopathic' and male-specific therapeutic options are sparse. Given the crucial role of the follicle-stimulating hormone (FSH) for spermatogenesis, FSH is used empirically to improve semen parameters. Furthermore, a recently updated Cochrane review points to a beneficial effect of FSH treatment in idiopathic infertile men on spontaneous pregnancy rates. However, since response to FSH varies strongly even in selected patients and given the lack of powerful evidence of FSH treatment regimens, intra-cytoplasmic spermatozoa injection (ICSI) is widely used in idiopathic male infertility, though the treatment burden is high for the couple and it entails considerable costs and some risks. Single nucleotide polymorphisms (SNPs) within FSH ligand/receptor genes (FSHB/FSHR), significantly influencing reproductive parameters in men, represent promising candidates to serve as pharmacogenetic markers to improve prediction of response to FSH. However, there is an evident lack of information which patients should be treated and how many patients in an andrological outpatient clinic would be eligible for such a treatment, a crucial decision criterion for clinicians and also pharmaceutical industry to start such a pharmacogenetic intervention therapy. After screening our andrological patient cohort, we present a realistic scenario and a basis for further prospective studies using FSH in idiopathic infertile men." @default.
• W2179755779 created "2016-06-24" @default.
• W2179755779 creator A5022099945 @default.
• W2179755779 creator A5048402117 @default.
• W2179755779 creator A5055275116 @default.
• W2179755779 creator A5059793960 @default.
• W2179755779 date "2015-10-07" @default.
• W2179755779 modified "2023-10-09" @default.
• W2179755779 title "<i>FSHB</i>-211G>T stratification for follicle-stimulating hormone treatment of male infertility patients: making the case for a pharmacogenetic approach in genetic functional secondary hypogonadism" @default.
• W2179755779 cites W138028103 @default.
• W2179755779 cites W1867714673 @default.
• W2179755779 cites W1965898781 @default.
• W2179755779 cites W1968773008 @default.
• W2179755779 cites W1969720894 @default.
• W2179755779 cites W1976965403 @default.
• W2179755779 cites W2004082379 @default.
• W2179755779 cites W2005549377 @default.
• W2179755779 cites W2022999286 @default.
• W2179755779 cites W2023369065 @default.
• W2179755779 cites W2024632745 @default.
• W2179755779 cites W2040914352 @default.
• W2179755779 cites W2055676771 @default.
• W2179755779 cites W2064721256 @default.
• W2179755779 cites W2080969392 @default.
• W2179755779 cites W2081459643 @default.
• W2179755779 cites W2084349851 @default.
• W2179755779 cites W2090423690 @default.
• W2179755779 cites W2096181838 @default.
• W2179755779 cites W2101233630 @default.
• W2179755779 cites W2110119053 @default.
• W2179755779 cites W2113947100 @default.
• W2179755779 cites W2123341694 @default.
• W2179755779 cites W2125102812 @default.
• W2179755779 cites W2126503856 @default.
• W2179755779 cites W2131485340 @default.
• W2179755779 cites W2140486768 @default.
• W2179755779 cites W2169601716 @default.
• W2179755779 cites W2169624100 @default.
• W2179755779 cites W2259773493 @default.
• W2179755779 cites W327137974 @default.
• W2179755779 cites W4241597726 @default.
• W2179755779 doi "https://doi.org/10.1111/andr.12094" @default.
• W2179755779 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26445243" @default.
• W2179755779 hasPublicationYear "2015" @default.
• W2179755779 type Work @default.
• W2179755779 sameAs 2179755779 @default.
• W2179755779 citedByCount "20" @default.
• W2179755779 countsByYear W21797557792016 @default.
• W2179755779 countsByYear W21797557792017 @default.
• W2179755779 countsByYear W21797557792018 @default.
• W2179755779 countsByYear W21797557792019 @default.
• W2179755779 countsByYear W21797557792020 @default.
• W2179755779 countsByYear W21797557792021 @default.
• W2179755779 countsByYear W21797557792022 @default.
• W2179755779 countsByYear W21797557792023 @default.
• W2179755779 crossrefType "journal-article" @default.
• W2179755779 hasAuthorship W2179755779A5022099945 @default.
• W2179755779 hasAuthorship W2179755779A5048402117 @default.
• W2179755779 hasAuthorship W2179755779A5055275116 @default.
• W2179755779 hasAuthorship W2179755779A5059793960 @default.
• W2179755779 hasBestOaLocation W21797557791 @default.
• W2179755779 hasConcept C104317684 @default.
• W2179755779 hasConcept C126322002 @default.
• W2179755779 hasConcept C135763542 @default.
• W2179755779 hasConcept C143998085 @default.
• W2179755779 hasConcept C2777338322 @default.
• W2179755779 hasConcept C2777688143 @default.
• W2179755779 hasConcept C2778575703 @default.
• W2179755779 hasConcept C2779234561 @default.
• W2179755779 hasConcept C2779279165 @default.
• W2179755779 hasConcept C29456083 @default.
• W2179755779 hasConcept C54355233 @default.
• W2179755779 hasConcept C55775858 @default.
• W2179755779 hasConcept C60644358 @default.
• W2179755779 hasConcept C71315377 @default.
• W2179755779 hasConcept C71924100 @default.
• W2179755779 hasConcept C86803240 @default.
• W2179755779 hasConceptScore W2179755779C104317684 @default.
• W2179755779 hasConceptScore W2179755779C126322002 @default.
• W2179755779 hasConceptScore W2179755779C135763542 @default.
• W2179755779 hasConceptScore W2179755779C143998085 @default.
• W2179755779 hasConceptScore W2179755779C2777338322 @default.
• W2179755779 hasConceptScore W2179755779C2777688143 @default.
• W2179755779 hasConceptScore W2179755779C2778575703 @default.
• W2179755779 hasConceptScore W2179755779C2779234561 @default.
• W2179755779 hasConceptScore W2179755779C2779279165 @default.
• W2179755779 hasConceptScore W2179755779C29456083 @default.
• W2179755779 hasConceptScore W2179755779C54355233 @default.
• W2179755779 hasConceptScore W2179755779C55775858 @default.
• W2179755779 hasConceptScore W2179755779C60644358 @default.
• W2179755779 hasConceptScore W2179755779C71315377 @default.
• W2179755779 hasConceptScore W2179755779C71924100 @default.
• W2179755779 hasConceptScore W2179755779C86803240 @default.
• W2179755779 hasFunder F4320322957 @default.
• W2179755779 hasIssue "6" @default.
• W2179755779 hasLocation W21797557791 @default.
• W2179755779 hasLocation W21797557792 @default.
• W2179755779 hasOpenAccess W2179755779 @default.

• next