FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2179862011> ?p ?o ?g. }

• W2179862011 endingPage "409" @default.
• W2179862011 startingPage "396" @default.
• W2179862011 abstract "Systemic lupus erythematosus is a heterogeneous autoimmune disease marked by the presence of pathogenic autoantibodies, immune dysregulation, and chronic inflammation that may lead to increased morbidity and early mortality from end-organ damage. More than half of all systemic lupus erythematosus patients will develop lupus nephritis. Genetic-association studies have identified more than 50 polymorphisms that contribute to lupus nephritis pathogenesis, including genetic variants associated with altered programmed cell death and defective immune clearance of programmed cell death debris. These variants may support the generation of autoantibody-containing immune complexes that contribute to lupus nephritis. Genetic variants associated with lupus nephritis also affect the initial phase of innate immunity and the amplifying, adaptive phase of the immune response. Finally, genetic variants associated with the kidney-specific effector response may influence end-organ damage and the progression to end-stage renal disease and death. This review discusses genetic insights of key pathogenic processes and pathways that may lead to lupus nephritis, as well as the clinical implications of these findings as they apply to recent advances in biologic therapies." @default.
• W2179862011 created "2016-06-24" @default.
• W2179862011 creator A5065514371 @default.
• W2179862011 creator A5088206527 @default.
• W2179862011 date "2015-09-01" @default.
• W2179862011 modified "2023-10-05" @default.
• W2179862011 title "Genetics of Lupus Nephritis: Clinical Implications" @default.
• W2179862011 cites W109573355 @default.
• W2179862011 cites W1572453246 @default.
• W2179862011 cites W1855823282 @default.
• W2179862011 cites W1912915587 @default.
• W2179862011 cites W1917720330 @default.
• W2179862011 cites W1926638744 @default.
• W2179862011 cites W1934676729 @default.
• W2179862011 cites W1938487222 @default.
• W2179862011 cites W1964602672 @default.
• W2179862011 cites W1965830188 @default.
• W2179862011 cites W1968227843 @default.
• W2179862011 cites W1969773043 @default.
• W2179862011 cites W1970963947 @default.
• W2179862011 cites W1971833707 @default.
• W2179862011 cites W1974553402 @default.
• W2179862011 cites W1976237335 @default.
• W2179862011 cites W1979586231 @default.
• W2179862011 cites W1979897867 @default.
• W2179862011 cites W1980174384 @default.
• W2179862011 cites W1981352846 @default.
• W2179862011 cites W1982983059 @default.
• W2179862011 cites W1982992324 @default.
• W2179862011 cites W1983648426 @default.
• W2179862011 cites W1987518110 @default.
• W2179862011 cites W1989038982 @default.
• W2179862011 cites W1989236531 @default.
• W2179862011 cites W1989273660 @default.
• W2179862011 cites W1989791234 @default.
• W2179862011 cites W1997088602 @default.
• W2179862011 cites W1997210789 @default.
• W2179862011 cites W1998369476 @default.
• W2179862011 cites W1999398455 @default.
• W2179862011 cites W2000054082 @default.
• W2179862011 cites W2000138729 @default.
• W2179862011 cites W2002116270 @default.
• W2179862011 cites W2004112473 @default.
• W2179862011 cites W2005375258 @default.
• W2179862011 cites W2010160850 @default.
• W2179862011 cites W2012762763 @default.
• W2179862011 cites W2015067566 @default.
• W2179862011 cites W2017347101 @default.
• W2179862011 cites W2021657063 @default.
• W2179862011 cites W2021944030 @default.
• W2179862011 cites W2023138787 @default.
• W2179862011 cites W2027016772 @default.
• W2179862011 cites W2028621860 @default.
• W2179862011 cites W2029120629 @default.
• W2179862011 cites W2029995436 @default.
• W2179862011 cites W2032349776 @default.
• W2179862011 cites W2035996425 @default.
• W2179862011 cites W2036425763 @default.
• W2179862011 cites W2036971846 @default.
• W2179862011 cites W2037461172 @default.
• W2179862011 cites W2037655025 @default.
• W2179862011 cites W2038002231 @default.
• W2179862011 cites W2039506264 @default.
• W2179862011 cites W2042187887 @default.
• W2179862011 cites W2045466504 @default.
• W2179862011 cites W2049247148 @default.
• W2179862011 cites W2051569082 @default.
• W2179862011 cites W2057872394 @default.
• W2179862011 cites W2059705136 @default.
• W2179862011 cites W2061976026 @default.
• W2179862011 cites W2062906411 @default.
• W2179862011 cites W2064813520 @default.
• W2179862011 cites W2065762732 @default.
• W2179862011 cites W2068293342 @default.
• W2179862011 cites W2072310856 @default.
• W2179862011 cites W2072577743 @default.
• W2179862011 cites W2072803699 @default.
• W2179862011 cites W2072910204 @default.
• W2179862011 cites W2075283457 @default.
• W2179862011 cites W2076538528 @default.
• W2179862011 cites W2077388406 @default.
• W2179862011 cites W2078490531 @default.
• W2179862011 cites W2082210523 @default.
• W2179862011 cites W2085406842 @default.
• W2179862011 cites W2087265576 @default.
• W2179862011 cites W2090343544 @default.
• W2179862011 cites W2091018161 @default.
• W2179862011 cites W2091156747 @default.
• W2179862011 cites W2094319086 @default.
• W2179862011 cites W2094328608 @default.
• W2179862011 cites W2096367702 @default.
• W2179862011 cites W2097326893 @default.
• W2179862011 cites W2099704507 @default.
• W2179862011 cites W2100186575 @default.
• W2179862011 cites W2100336973 @default.
• W2179862011 cites W2100516310 @default.
• W2179862011 cites W2103306578 @default.
• W2179862011 cites W2103532849 @default.

• next