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- W2179934229 abstract "Use of feed antibiotics as growth promoters for control of pathogens associated with monogastric food animal morbidity and mortality has contributed to the development of antimicrobial resistance, which has now become a threat to public health on a global scale. Presently, a number of alternative feed additives have been developed and are divided into two major categories, including 1) the ones that are supposed to directly and indirectly control pathogenic bacterial proliferation; and 2) the other ones that are intended to up-regulate host gut mucosal trophic growth, whole body growth performance and active immunity. A thorough review of literature reports reveal that efficacy responses of current alternative feed additives in replacing feed antibiotics to improve performances and gut health are generally inconsistent dependent upon experimental conditions. Current alternative feed additives typically have no direct detoxification effects on endotoxin lipopolysaccharides (LPS) and this is likely the major reason that their effects are limited. It is now understood that pathogenic bacteria mediate their negative effects largely through LPS interactions with toll-like receptor 4, causing immune responses and infectious diseases. Therefore, disruptive biological strategies and a novel and new generation of feed additives need to be developed to replace feed antibiotic growth promoters and to directly and effectively detoxify the endotoxin LPS and improve gut health and performance in monogastric food animals." @default.
- W2179934229 created "2016-06-24" @default.
- W2179934229 creator A5003780805 @default.
- W2179934229 creator A5008001720 @default.
- W2179934229 date "2015-09-01" @default.
- W2179934229 modified "2023-10-01" @default.
- W2179934229 title "Novel and disruptive biological strategies for resolving gut health challenges in monogastric food animal production" @default.
- W2179934229 cites W1493444364 @default.
- W2179934229 cites W1590329869 @default.
- W2179934229 cites W1878695667 @default.
- W2179934229 cites W1884278958 @default.
- W2179934229 cites W1903344188 @default.
- W2179934229 cites W1912578996 @default.
- W2179934229 cites W1928849416 @default.
- W2179934229 cites W1968772038 @default.
- W2179934229 cites W1984795764 @default.
- W2179934229 cites W2004585293 @default.
- W2179934229 cites W2010708340 @default.
- W2179934229 cites W2012968633 @default.
- W2179934229 cites W2016573192 @default.
- W2179934229 cites W2018408225 @default.
- W2179934229 cites W2021032925 @default.
- W2179934229 cites W2025468966 @default.
- W2179934229 cites W2033283307 @default.
- W2179934229 cites W2035150578 @default.
- W2179934229 cites W2035885128 @default.
- W2179934229 cites W2037569213 @default.
- W2179934229 cites W2039405310 @default.
- W2179934229 cites W2039880692 @default.
- W2179934229 cites W2043041439 @default.
- W2179934229 cites W2044948009 @default.
- W2179934229 cites W2046501778 @default.
- W2179934229 cites W2048066772 @default.
- W2179934229 cites W2050342825 @default.
- W2179934229 cites W2054766392 @default.
- W2179934229 cites W2055334054 @default.
- W2179934229 cites W2060500245 @default.
- W2179934229 cites W2064668487 @default.
- W2179934229 cites W2066915580 @default.
- W2179934229 cites W2069766106 @default.
- W2179934229 cites W2071108985 @default.
- W2179934229 cites W2071606198 @default.
- W2179934229 cites W2071712057 @default.
- W2179934229 cites W2074194511 @default.
- W2179934229 cites W2074306163 @default.
- W2179934229 cites W2087907395 @default.
- W2179934229 cites W2105427918 @default.
- W2179934229 cites W2108599358 @default.
- W2179934229 cites W2111281542 @default.
- W2179934229 cites W2111951615 @default.
- W2179934229 cites W2115809399 @default.
- W2179934229 cites W2126311363 @default.
- W2179934229 cites W2126795224 @default.
- W2179934229 cites W2126979693 @default.
- W2179934229 cites W2128616554 @default.
- W2179934229 cites W2129319296 @default.
- W2179934229 cites W2132219626 @default.
- W2179934229 cites W2132291934 @default.
- W2179934229 cites W2134406462 @default.
- W2179934229 cites W2134830426 @default.
- W2179934229 cites W2138618535 @default.
- W2179934229 cites W2139555462 @default.
- W2179934229 cites W2140932205 @default.
- W2179934229 cites W2143194729 @default.
- W2179934229 cites W2145043315 @default.
- W2179934229 cites W2146434896 @default.
- W2179934229 cites W2146948320 @default.
- W2179934229 cites W2151436324 @default.
- W2179934229 cites W2151450070 @default.
- W2179934229 cites W2153827707 @default.
- W2179934229 cites W2154880196 @default.
- W2179934229 cites W2155367962 @default.
- W2179934229 cites W2161525261 @default.
- W2179934229 cites W2166323731 @default.
- W2179934229 cites W2171286410 @default.
- W2179934229 cites W2171481693 @default.
- W2179934229 cites W2183237929 @default.
- W2179934229 cites W2242369056 @default.
- W2179934229 cites W2314132209 @default.
- W2179934229 cites W2335063073 @default.
- W2179934229 cites W243241630 @default.
- W2179934229 cites W322909982 @default.
- W2179934229 cites W58014301 @default.
- W2179934229 cites W923772521 @default.
- W2179934229 doi "https://doi.org/10.1016/j.aninu.2015.10.002" @default.
- W2179934229 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5945940" @default.
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- W2179934229 hasPublicationYear "2015" @default.
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