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• W2180293863 abstract "Antimicrobial peptides and complement components contribute to host defense as well as inflammation and tissue injury in the respiratory tract. The airway epithelial surface is the main site of action of these immune effectors, and airway epithelial cells contribute markedly to their local production. Whereas both antimicrobial peptides and complement display overlapping functions, it is increasingly clear that both effector mechanisms also interact. Furthermore, excessive or uncontrolled release of antimicrobial peptides as well as complement activation may contribute to inflammatory lung diseases. Therefore, further knowledge of interactions between these systems may provide more insight into the pathogenesis of a range of lung diseases. In this review, recent findings on the functions, collaborations and other interactions between antimicrobial peptides and complement are discussed with a specific focus on the airway epithelium." @default.
• W2180293863 created "2016-06-24" @default.
• W2180293863 creator A5070088574 @default.
• W2180293863 date "2015-11-01" @default.
• W2180293863 modified "2023-10-14" @default.
• W2180293863 title "Parallel activities and interactions between antimicrobial peptides and complement in host defense at the airway epithelial surface" @default.
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• W2180293863 doi "https://doi.org/10.1016/j.molimm.2015.07.030" @default.
• W2180293863 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26597202" @default.
• W2180293863 hasPublicationYear "2015" @default.
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