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- W2180312295 abstract "We have designed and synthesized a series of novel molecules having a residue of a classical NSAID and an antioxidant moiety, both attached through amide bonds to a known nootropic structure, an L-proline, trans-4-hydroxy-L-proline or DL-pipecolinic acid residue. The compounds were found to retain anti-inflammatory and antioxidant activities, to acquire hypocholesterolemic action, and to possess a greatly reduced gastrointestinal toxicity. The novel molecules could find useful applications, among others, in slowing the progression or delaying the onset of neurodegenerative diseases." @default.
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- W2180312295 date "2006-02-01" @default.
- W2180312295 modified "2023-09-25" @default.
- W2180312295 title "Synthesis and pharmacochemical study of novel polyfunctional molecules combining anti-inflammatory, antioxidant, and hypocholesterolemic properties" @default.
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- W2180312295 doi "https://doi.org/10.1016/j.bmcl.2005.11.027" @default.
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