Matches in SemOpenAlex for { <https://semopenalex.org/work/W2180656997> ?p ?o ?g. }
- W2180656997 endingPage "203" @default.
- W2180656997 startingPage "189" @default.
- W2180656997 abstract "Several diamino quinoxalines were designed, synthesized and evaluated as anti-tumor agents. Two compounds showed the most potent cytotoxic activities against the leukemia CCRF-CEM cell line (GI50 < 0.01 μM) and the ovarian cancer cell line OVCAR-4 (GI50 = 0.03 μM), respectively, with comparable/better activities than Methotrexate (MTX). Docking calculations of the complexes of hDHFR with the most active compounds identified the binding mode of the described molecules with respect to MTX." @default.
- W2180656997 created "2016-06-24" @default.
- W2180656997 creator A5003902997 @default.
- W2180656997 creator A5027572844 @default.
- W2180656997 creator A5067042371 @default.
- W2180656997 creator A5073099287 @default.
- W2180656997 creator A5085714078 @default.
- W2180656997 date "2008-01-01" @default.
- W2180656997 modified "2023-10-17" @default.
- W2180656997 title "Synthesis of N-(5,7-diamino-3-phenyl-quinoxalin-2-yl)-3,4,5-substituted anilines and N-[4[(5,7-diamino-3-phenylquinoxalin-2-yl)amino]benzoyl]-l-glutamic acid diethyl ester: Evaluation of in vitro anti-cancer and anti-folate activities" @default.
- W2180656997 cites W1508681581 @default.
- W2180656997 cites W1510646666 @default.
- W2180656997 cites W1525329624 @default.
- W2180656997 cites W1981068972 @default.
- W2180656997 cites W1982681722 @default.
- W2180656997 cites W1993353893 @default.
- W2180656997 cites W1995808589 @default.
- W2180656997 cites W2030298366 @default.
- W2180656997 cites W2033478780 @default.
- W2180656997 cites W2049072597 @default.
- W2180656997 cites W2052524067 @default.
- W2180656997 cites W2056022007 @default.
- W2180656997 cites W2059251164 @default.
- W2180656997 cites W2063073890 @default.
- W2180656997 cites W2064526852 @default.
- W2180656997 cites W2067254651 @default.
- W2180656997 cites W2085363005 @default.
- W2180656997 cites W2090453586 @default.
- W2180656997 cites W2093983183 @default.
- W2180656997 cites W2109689528 @default.
- W2180656997 cites W2130479394 @default.
- W2180656997 cites W2132717858 @default.
- W2180656997 cites W2155208683 @default.
- W2180656997 cites W2158534713 @default.
- W2180656997 cites W2165614853 @default.
- W2180656997 cites W2167395325 @default.
- W2180656997 cites W2177477958 @default.
- W2180656997 cites W2180584108 @default.
- W2180656997 cites W2257325031 @default.
- W2180656997 cites W2508865393 @default.
- W2180656997 cites W2511082925 @default.
- W2180656997 cites W2511518509 @default.
- W2180656997 cites W3048804492 @default.
- W2180656997 cites W3101766453 @default.
- W2180656997 cites W2045904561 @default.
- W2180656997 doi "https://doi.org/10.1016/j.ejmech.2007.03.035" @default.
- W2180656997 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17532099" @default.
- W2180656997 hasPublicationYear "2008" @default.
- W2180656997 type Work @default.
- W2180656997 sameAs 2180656997 @default.
- W2180656997 citedByCount "13" @default.
- W2180656997 countsByYear W21806569972012 @default.
- W2180656997 countsByYear W21806569972013 @default.
- W2180656997 countsByYear W21806569972014 @default.
- W2180656997 countsByYear W21806569972015 @default.
- W2180656997 countsByYear W21806569972017 @default.
- W2180656997 countsByYear W21806569972018 @default.
- W2180656997 countsByYear W21806569972019 @default.
- W2180656997 countsByYear W21806569972021 @default.
- W2180656997 countsByYear W21806569972022 @default.
- W2180656997 crossrefType "journal-article" @default.
- W2180656997 hasAuthorship W2180656997A5003902997 @default.
- W2180656997 hasAuthorship W2180656997A5027572844 @default.
- W2180656997 hasAuthorship W2180656997A5067042371 @default.
- W2180656997 hasAuthorship W2180656997A5073099287 @default.
- W2180656997 hasAuthorship W2180656997A5085714078 @default.
- W2180656997 hasConcept C178790620 @default.
- W2180656997 hasConcept C185592680 @default.
- W2180656997 hasConcept C32909587 @default.
- W2180656997 hasConcept C54355233 @default.
- W2180656997 hasConcept C71240020 @default.
- W2180656997 hasConcept C81885089 @default.
- W2180656997 hasConcept C86803240 @default.
- W2180656997 hasConceptScore W2180656997C178790620 @default.
- W2180656997 hasConceptScore W2180656997C185592680 @default.
- W2180656997 hasConceptScore W2180656997C32909587 @default.
- W2180656997 hasConceptScore W2180656997C54355233 @default.
- W2180656997 hasConceptScore W2180656997C71240020 @default.
- W2180656997 hasConceptScore W2180656997C81885089 @default.
- W2180656997 hasConceptScore W2180656997C86803240 @default.
- W2180656997 hasIssue "1" @default.
- W2180656997 hasLocation W21806569971 @default.
- W2180656997 hasLocation W21806569972 @default.
- W2180656997 hasOpenAccess W2180656997 @default.
- W2180656997 hasPrimaryLocation W21806569971 @default.
- W2180656997 hasRelatedWork W1963808681 @default.
- W2180656997 hasRelatedWork W1970587968 @default.
- W2180656997 hasRelatedWork W1970974546 @default.
- W2180656997 hasRelatedWork W1996140555 @default.
- W2180656997 hasRelatedWork W2056033865 @default.
- W2180656997 hasRelatedWork W2070588828 @default.
- W2180656997 hasRelatedWork W2083085294 @default.
- W2180656997 hasRelatedWork W2950635040 @default.
- W2180656997 hasRelatedWork W2951170475 @default.
- W2180656997 hasRelatedWork W2951247485 @default.
- W2180656997 hasVolume "43" @default.
- W2180656997 isParatext "false" @default.
- W2180656997 isRetracted "false" @default.