Matches in SemOpenAlex for { <https://semopenalex.org/work/W2181321811> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2181321811 endingPage "C1416" @default.
- W2181321811 startingPage "C1411" @default.
- W2181321811 abstract "Alterations in the competency of the creatine kinase system elicit numerous structural and metabolic compensations, including changes in purine nucleotide metabolism. We evaluated molecular and kinetic changes in AMP deaminase from skeletal muscles of mice deficient in either cytosolic creatine kinase alone (M-CK-/-) or also deficient in mitochondrial creatine kinase (CK-/-) compared with wild type. We found that predominantly fast-twitch muscle, but not slow-twitch muscle, from both M-CK-/- and CK-/- mice had much lower AMP deaminase; the quantity of AMP deaminase detected by Western blot was correspondingly lower, whereas AMP deaminase-1 (AMPD1) gene expression was unchanged. Kinetic analysis of AMP deaminase from mixed muscle revealed negative cooperativity that was significantly greater in creatine kinase deficiencies. Treatment of AMP deaminase with acid phosphatase abolished negative cooperative behavior, indicating that a phosphorylation-dephosphorylation cycle may be important in the regulation of AMP deaminase." @default.
- W2181321811 created "2016-06-24" @default.
- W2181321811 creator A5003961563 @default.
- W2181321811 creator A5012748294 @default.
- W2181321811 creator A5060858832 @default.
- W2181321811 creator A5067994359 @default.
- W2181321811 date "1998-05-01" @default.
- W2181321811 modified "2023-10-17" @default.
- W2181321811 title "Alterations in AMP deaminase activity and kinetics in skeletal muscle of creatine kinase-deficient mice" @default.
- W2181321811 cites W105155487 @default.
- W2181321811 cites W1561284129 @default.
- W2181321811 cites W1849159432 @default.
- W2181321811 cites W1967686595 @default.
- W2181321811 cites W1969656420 @default.
- W2181321811 cites W1978608872 @default.
- W2181321811 cites W1983090416 @default.
- W2181321811 cites W1994831592 @default.
- W2181321811 cites W2026316964 @default.
- W2181321811 cites W2032498082 @default.
- W2181321811 cites W2034349012 @default.
- W2181321811 cites W2036832507 @default.
- W2181321811 cites W2051974797 @default.
- W2181321811 cites W2063980449 @default.
- W2181321811 cites W2097831558 @default.
- W2181321811 cites W2104848153 @default.
- W2181321811 cites W2128021010 @default.
- W2181321811 cites W2170817369 @default.
- W2181321811 cites W2218812945 @default.
- W2181321811 cites W2263689279 @default.
- W2181321811 cites W2278101261 @default.
- W2181321811 cites W2283944439 @default.
- W2181321811 cites W2338550813 @default.
- W2181321811 cites W2342471521 @default.
- W2181321811 cites W954944586 @default.
- W2181321811 doi "https://doi.org/10.1152/ajpcell.1998.274.5.c1411" @default.
- W2181321811 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9612229" @default.
- W2181321811 hasPublicationYear "1998" @default.
- W2181321811 type Work @default.
- W2181321811 sameAs 2181321811 @default.
- W2181321811 citedByCount "18" @default.
- W2181321811 countsByYear W21813218112015 @default.
- W2181321811 countsByYear W21813218112020 @default.
- W2181321811 countsByYear W21813218112022 @default.
- W2181321811 crossrefType "journal-article" @default.
- W2181321811 hasAuthorship W2181321811A5003961563 @default.
- W2181321811 hasAuthorship W2181321811A5012748294 @default.
- W2181321811 hasAuthorship W2181321811A5060858832 @default.
- W2181321811 hasAuthorship W2181321811A5067994359 @default.
- W2181321811 hasConcept C126322002 @default.
- W2181321811 hasConcept C134018914 @default.
- W2181321811 hasConcept C165912504 @default.
- W2181321811 hasConcept C178666793 @default.
- W2181321811 hasConcept C181199279 @default.
- W2181321811 hasConcept C181912034 @default.
- W2181321811 hasConcept C185592680 @default.
- W2181321811 hasConcept C2779896295 @default.
- W2181321811 hasConcept C2779959927 @default.
- W2181321811 hasConcept C34628245 @default.
- W2181321811 hasConcept C36880943 @default.
- W2181321811 hasConcept C55493867 @default.
- W2181321811 hasConcept C71924100 @default.
- W2181321811 hasConcept C86803240 @default.
- W2181321811 hasConceptScore W2181321811C126322002 @default.
- W2181321811 hasConceptScore W2181321811C134018914 @default.
- W2181321811 hasConceptScore W2181321811C165912504 @default.
- W2181321811 hasConceptScore W2181321811C178666793 @default.
- W2181321811 hasConceptScore W2181321811C181199279 @default.
- W2181321811 hasConceptScore W2181321811C181912034 @default.
- W2181321811 hasConceptScore W2181321811C185592680 @default.
- W2181321811 hasConceptScore W2181321811C2779896295 @default.
- W2181321811 hasConceptScore W2181321811C2779959927 @default.
- W2181321811 hasConceptScore W2181321811C34628245 @default.
- W2181321811 hasConceptScore W2181321811C36880943 @default.
- W2181321811 hasConceptScore W2181321811C55493867 @default.
- W2181321811 hasConceptScore W2181321811C71924100 @default.
- W2181321811 hasConceptScore W2181321811C86803240 @default.
- W2181321811 hasIssue "5" @default.
- W2181321811 hasLocation W21813218111 @default.
- W2181321811 hasLocation W21813218112 @default.
- W2181321811 hasOpenAccess W2181321811 @default.
- W2181321811 hasPrimaryLocation W21813218111 @default.
- W2181321811 hasRelatedWork W185666144 @default.
- W2181321811 hasRelatedWork W1974568996 @default.
- W2181321811 hasRelatedWork W2016840789 @default.
- W2181321811 hasRelatedWork W2081376013 @default.
- W2181321811 hasRelatedWork W2181321811 @default.
- W2181321811 hasRelatedWork W2284240597 @default.
- W2181321811 hasRelatedWork W2309978229 @default.
- W2181321811 hasRelatedWork W2320914227 @default.
- W2181321811 hasRelatedWork W2463478234 @default.
- W2181321811 hasRelatedWork W4383602876 @default.
- W2181321811 hasVolume "274" @default.
- W2181321811 isParatext "false" @default.
- W2181321811 isRetracted "false" @default.
- W2181321811 magId "2181321811" @default.
- W2181321811 workType "article" @default.