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- W2181329496 abstract "1showed that patients with narcolepsy have reduced concentrations of hypocretin (orexin) in their cerebrospinal fluid. Because hypocretins stimulate food intake in animal models, Siegel hypothesised 2 that patients with narcolepsy should be lean, rather than obese. However, in an earlier report Honda and colleagues 3 suggest that in patients with narcolepsy the frequency of obesity and of non-insulin dependent diabetes is increased compared with a non-healthy control group of psychiatric patients. To gather more reliable information, we retrospectively identified all patients of 14–70 years who had narcolepsy, and who were treated in the Max-Planck-Institute of Psychiatry, Munich, Germany, between 1988 and 1999 (n=45). We selected all patients with: excessive daytime sleepiness; cataplectic attacks;" @default.
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- W2181329496 date "2000-01-01" @default.
- W2181329496 modified "2023-09-27" @default.
- W2181329496 title "Increased body-mass index in patients with narcolepsy" @default.
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