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- W2181343313 abstract "Films of polyvinylidene fluoride (PVDF) were treated in a microwave plasma, using different discharge gases (N2, N2/H2, and CO2), for the treatment conditions established as being the most appropriate for functionalizing the PVDF surface, in order to further coat it with an albumin layer. To evidence the physical adsorption of protein, several methods were used (gravimetric measurements, contact angle measurements, AFM and FTIR spectroscopy). It was found that plasma treatment determines a drastic increase in the albumin quantity adhering to PVDF surfaces (especially when N2/H2 is used as discharge gas). After coating the plasma pre-treated PVDF film surface with proteins, the hydrophilic character of the polymer increased. As albumin-treated surfaces are resistant to platelet adhesion, an enhanced tolerance towards biological fluids and an increased haemocompatibility are expected. In the same time, the albumin increases the number of functional groups (−NH2 and −COOH) on the polymer surface, for binding other bioactive molecules, thus extending the polymer applicability. Plasma treatment of PVDF in a microwave discharge, followed by coating with bovine serum albumin proved to be very useful for the appropriate modification of its surface properties, thus leading to a possible increase in the biocompatibility characteristics of the polymer." @default.
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- W2181343313 date "2011-01-01" @default.
- W2181343313 modified "2023-09-25" @default.
- W2181343313 title "ALBUMIN IMMOBILIZATION ON POLYVINYLIDENE FLUORIDE SURFACES" @default.
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