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- W2181373457 abstract "Microgonotropens consist of a minor groove binding moiety functionalized with alkylamine side chains which are protonated and positively charged at neutral pH and capable of forming electrostatic bonds with the negatively charged phosphodiester backbone of DNA. We have investigated the interactions between microgonotropens and double-stranded DNA by a combination of fluorescence, ultraviolet, and nuclear magnetic resonance spectroscopy. Our work reveals why microgonotropens are such potent inhibitors of the binding of transcription factors to their DNA binding sites." @default.
- W2181373457 created "2016-06-24" @default.
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- W2181373457 date "2002-01-01" @default.
- W2181373457 modified "2023-09-27" @default.
- W2181373457 title "Recognition in the Minor Groove of Double-Stranded DNA by" @default.
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