Matches in SemOpenAlex for { <https://semopenalex.org/work/W2181396750> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2181396750 abstract "This paper does not present finished work but discusses a current problem faced by the EMEA in detecting when a new safety problem with a marketed pharmaceutical product is emerging. This detection is based on analysis of a very large database of spontaneous reports by healthcare professionals. The mixture of complexity but also known structure within the data appear to call for a combination of formal statistical modeling and data-mining. EudraVigilance contains two reporting modules: the EudraVigilance Post Marketing module (EVPM) collects reports of suspected adverse drug reactions associated with medicinal products authorized for use in the EEA while the EudraVigilance Clinical Trials module collects such reports from pre-authorisation drug trials. The work reported here is the planning phase of a project to decide which of the many thousands of reports received by EVPM each year represent true adverse drug reactions (ADRs) and which are prompted by chance temporal associations of clinical adverse events (AEs) and use of a medicinal product. A process referred to as 'signal detection'. The main challenges associated with the work are the very large size of the dataset, the arbitrarily many different codes which may be used for medicinal products and for adverse events, and the complex social and clinical mechanisms underlying the reporting process. As part of a tender to redesign the EudraVigilance Data Warehouse system in 2005 the EMEA have adopted SAS as the analysis package within which to build the signal detection algorithms." @default.
- W2181396750 created "2016-06-24" @default.
- W2181396750 creator A5061051737 @default.
- W2181396750 date "2005-01-01" @default.
- W2181396750 modified "2023-09-27" @default.
- W2181396750 title "Signal Detection in EudraVigilance" @default.
- W2181396750 cites W1981809734 @default.
- W2181396750 cites W2039594635 @default.
- W2181396750 cites W2064716383 @default.
- W2181396750 cites W2104442633 @default.
- W2181396750 cites W2140742150 @default.
- W2181396750 hasPublicationYear "2005" @default.
- W2181396750 type Work @default.
- W2181396750 sameAs 2181396750 @default.
- W2181396750 citedByCount "0" @default.
- W2181396750 crossrefType "journal-article" @default.
- W2181396750 hasAuthorship W2181396750A5061051737 @default.
- W2181396750 hasConcept C111919701 @default.
- W2181396750 hasConcept C112930515 @default.
- W2181396750 hasConcept C124101348 @default.
- W2181396750 hasConcept C127413603 @default.
- W2181396750 hasConcept C142724271 @default.
- W2181396750 hasConcept C18762648 @default.
- W2181396750 hasConcept C197934379 @default.
- W2181396750 hasConcept C2522767166 @default.
- W2181396750 hasConcept C2524010 @default.
- W2181396750 hasConcept C2777589142 @default.
- W2181396750 hasConcept C2780035454 @default.
- W2181396750 hasConcept C2993432071 @default.
- W2181396750 hasConcept C33923547 @default.
- W2181396750 hasConcept C41008148 @default.
- W2181396750 hasConcept C535046627 @default.
- W2181396750 hasConcept C57658597 @default.
- W2181396750 hasConcept C60644358 @default.
- W2181396750 hasConcept C71924100 @default.
- W2181396750 hasConcept C78519656 @default.
- W2181396750 hasConcept C86803240 @default.
- W2181396750 hasConcept C90673727 @default.
- W2181396750 hasConcept C98045186 @default.
- W2181396750 hasConcept C98274493 @default.
- W2181396750 hasConceptScore W2181396750C111919701 @default.
- W2181396750 hasConceptScore W2181396750C112930515 @default.
- W2181396750 hasConceptScore W2181396750C124101348 @default.
- W2181396750 hasConceptScore W2181396750C127413603 @default.
- W2181396750 hasConceptScore W2181396750C142724271 @default.
- W2181396750 hasConceptScore W2181396750C18762648 @default.
- W2181396750 hasConceptScore W2181396750C197934379 @default.
- W2181396750 hasConceptScore W2181396750C2522767166 @default.
- W2181396750 hasConceptScore W2181396750C2524010 @default.
- W2181396750 hasConceptScore W2181396750C2777589142 @default.
- W2181396750 hasConceptScore W2181396750C2780035454 @default.
- W2181396750 hasConceptScore W2181396750C2993432071 @default.
- W2181396750 hasConceptScore W2181396750C33923547 @default.
- W2181396750 hasConceptScore W2181396750C41008148 @default.
- W2181396750 hasConceptScore W2181396750C535046627 @default.
- W2181396750 hasConceptScore W2181396750C57658597 @default.
- W2181396750 hasConceptScore W2181396750C60644358 @default.
- W2181396750 hasConceptScore W2181396750C71924100 @default.
- W2181396750 hasConceptScore W2181396750C78519656 @default.
- W2181396750 hasConceptScore W2181396750C86803240 @default.
- W2181396750 hasConceptScore W2181396750C90673727 @default.
- W2181396750 hasConceptScore W2181396750C98045186 @default.
- W2181396750 hasConceptScore W2181396750C98274493 @default.
- W2181396750 hasLocation W21813967501 @default.
- W2181396750 hasOpenAccess W2181396750 @default.
- W2181396750 hasPrimaryLocation W21813967501 @default.
- W2181396750 hasRelatedWork W1987581851 @default.
- W2181396750 hasRelatedWork W2005259267 @default.
- W2181396750 hasRelatedWork W2019453867 @default.
- W2181396750 hasRelatedWork W2029917712 @default.
- W2181396750 hasRelatedWork W2035134373 @default.
- W2181396750 hasRelatedWork W2061611217 @default.
- W2181396750 hasRelatedWork W2408641126 @default.
- W2181396750 hasRelatedWork W2463683278 @default.
- W2181396750 hasRelatedWork W2620678239 @default.
- W2181396750 hasRelatedWork W2906409000 @default.
- W2181396750 hasRelatedWork W2951460057 @default.
- W2181396750 hasRelatedWork W2990385959 @default.
- W2181396750 hasRelatedWork W3007610090 @default.
- W2181396750 hasRelatedWork W3127021901 @default.
- W2181396750 hasRelatedWork W3137333611 @default.
- W2181396750 hasRelatedWork W3137855116 @default.
- W2181396750 hasRelatedWork W3146698598 @default.
- W2181396750 hasRelatedWork W40475248 @default.
- W2181396750 hasRelatedWork W2183101435 @default.
- W2181396750 hasRelatedWork W2823354532 @default.
- W2181396750 isParatext "false" @default.
- W2181396750 isRetracted "false" @default.
- W2181396750 magId "2181396750" @default.
- W2181396750 workType "article" @default.