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- W2181551687 abstract "(Channel catfish virus (CCV) causes a severe hemorrhagicdisease in channel catfish fry and fingerlings. CCV epizootics j associated withelevated water temperatures and high mortality rates. Survivorsof acute disease are latently infected with i virus. In this study, we investigated conditions effecting CCV pathogenesis and latency utilizing an experimental mersion model to simulate natural infection and a population of Arkansascatfish verified to have no prior CCV exposure, e resultsindicate that the Auburn-1 laboratorystrain is comparable to CCV field isolatesin virulenceand abilityto establish ent infection. The studyconfirms that water temperature and fish age effect susceptibility to acute infection. Twenty-four ek old fish were more susceptible to acute CCV infection at 28° C than at 24° C. Eight week old fish were susceptible to ease at 24° C and 28° C. Yearlingcatfish,although more resistant to acute disease,were susceptible to latent CCV infection. 2Vlatency was established as early as 27 days followingexperimental infection and maintained for at least one year post ection. The CCV infectionmodel describedin this report is usefulfor furtherinvestigation of CCV pathogenesis and latency and for evaluation of potential antiviral therapies." @default.
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- W2181551687 date "2003-01-01" @default.
- W2181551687 modified "2023-09-27" @default.
- W2181551687 title "Experimental Channel Catfish Virus Infection Mimics Natural Infection of Channel Catfish" @default.
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