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- W2181569462 abstract "The effect of several storage conditions on the permeability of pig skin was investigated. Three different storage conditions were studied, each at two temperatures: 4°C and -15°C. Skin was stored before dermatoming, after dermatoming, and after dermatoming and drying. The variability in the flux of watet and salicylic acid (SA), and their ratios (water/SA) over time, served as indicators for the change in the barrier properties of skin. It was found that stoting the skin after dermatoming at 4°C kept the permeability of the skin unchanged for four weeks. Storing the skin at a temperature of -15°C altered its permeation to water and SA significantly, however; when the skin was dried before storage, its stability at -15°C was improved. Monitoring the fluxes of two compounds of different polarities and their flux ratios over time is a more rigorous way of testing retention of the barrier integrity of skin than studying the change in flux of one molecule." @default.
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- W2181569462 date "1997-01-01" @default.
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- W2181569462 title "Dual-probe method for assessing skin barrier integrity: Effect of storage conditions on permeability of micro-Yucatan pig skin" @default.
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