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- W2181607156 abstract "PURPOSE. To perform a screening for potential adverse drug interactions (DIs) in patients hospitalized in the Clinic of Dermatology and Venereology at the University Hospital in Stara Zagora using available electronic resources, and identify the factors associated with their occurrence. PATIENTS AND METHODS. All consecutive inpatients admitted to the Clinic for the period March-September 2009 were screened for potential adverse DIs using an electronic drug interactions checker. Adverse DIs were classified into the following categories: “caution advised”, “monitor/modify therapy”, “avoid/use altenative” according to clinical management. RESULTS. A total of 157 patients were included in the study. Adverse DIs (77 in number) were detected in 40 patients. DIs from the category “Monitor/modify” were the prevalent type. The development of adverse DIs was significantly associated with a higher number of drugs (p=0.0001) and old age (p=0.0001). In two cases the adverse DI led to a manifest adverse drug reaction. DISCUSSION. Adverse DIs were found in a significant part of dermatology patients. The study confirmed the role of polypharmacy for DIs. Although adverse DIs rarely result in manifest ADRs, these ADRs can be of high clinical importance due to their severity thus justifying close monitoring for potential DIs." @default.
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- W2181607156 date "2010-01-01" @default.
- W2181607156 modified "2023-09-26" @default.
- W2181607156 title "SCREENING FOR ADVERSE DRUG INTERACTIONS IN DERMATOLOGY PATIENTS" @default.
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