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- W2181672157 abstract "This work aimed to determine if camphor oil has any protective properties to atrazine induced toxicity. To investigate this purpose, 40 Swiss albino male rats of 10 weeks old and 80-120g body weight were equally divided into four groups. Atrazine group orally administered 200 mg/kg, camphor group orally administered 30 mg/kg, atrazine and camphor group received 200mg atrazine and 30mg camphor on each other day for 30 days. Blood samples were collected from the retro orbital venous plexus of all animals before scarified and liver tissues were collected and preserved at -80°C. Plasma ALT, AST, SOD, MDA and total antioxidant capacity were measured in addition to testosterone and estradiol. Genomic DNA fragmentation was performed to hepatic tissues of all groups. Results revealed that treatment with camphor and/or atrazine or both increased levels of AST and decreased levels of ALT. Camphor oil decreased both testosterone and estradiol levels but atrazine increased testosterone levels. Camphor increased the aromatization of tesosterone to estradiol in atrazine and camphor group. Camphor alone decreased MDA and SOD levels but its combination with atrazine increased them also genomic DNA fragmentation was similar in both atrazine treated groups and camphor showed no protective effects.. In conclusion camphor has antioxidant properties but could not reduce the toxic effects of atrazine in rats." @default.
- W2181672157 created "2016-06-24" @default.
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- W2181672157 date "2014-01-01" @default.
- W2181672157 modified "2023-09-27" @default.
- W2181672157 title "Effects of Camphor on Hepatic Enzymes, Steroids and Antioxidant Capacity of Male Rats Intoxicated with Atrazine" @default.
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