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• W2181779690 abstract "Sixty-day static renewal bioassays were conducted to evaluate the chronic toxicity of the synthetic pyrethroid, fenvalerate to freshwater catfish Clarias gariepinus and the role of dietary supplementation of ascorbic acid to ameliorate the toxic effects of the pesticide. Bioassays were made using a 3X3 factorial design to test three concentrations of fenvalerate (0, 0.58, and 2.9 µg.L -1 ) and three levels of ascorbic acid (0, 50 and 100 mg/100 g diet). Chronic exposures to the sub-lethal concentrations of fenvalerate increased mortality and reduced growth of the fish in a dose-dependent way. Ascorbic acid concentrations decreased in the kidney and increased in the liver of the fish following chronic exposure to fenvalerate. Fish fed a dietary supplement of ascorbic acid showed higher growth and increased capacity to counteract the ill effects of fenvalerate. A supplement of 50 mg ascorbic acid per 100 g diet was found adequate to induce higher growth in control fish, while a higher concentration of ascorbic acid (100 mg/100 g diet) was necessary to counteract the effects of chronic exposure to fenvalerate. However, even the higher ascorbic acid supplement (100 mg/100 g diet) could not protect against the detrimental effects of 2.9 µg.L -1 fenvalerate." @default.
• W2181779690 created "2016-06-24" @default.
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• W2181779690 date "2006-01-01" @default.
• W2181779690 modified "2023-09-26" @default.
• W2181779690 title "DIETARY ASCORBIC ACID SUPPLEMENTATION TO AMELIORATE CHRONIC TOXICITY OF FENVALERATE TO CLARIAS GARIEPINUS" @default.
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