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- W2181877562 abstract "® ), which is available as a powder inhaler for oral inhalation. 10-12 Aclidinium, ipratropium, tiotropium, umeclidinium and umeclidinium/vilanterol are Food and Drug Administration (FDA)-approved for the maintenance treatment of bronchospasm associated with COPD, including chronic bronchitis and emphysema. Tiotropium is the only inhaled anticholinergic that is FDA-approved for reducing exacerbations associated with COPD. Ipratropium/albuterol is indicated for the treatment of bronchospasms associated with COPD in patients who require more than one bronchodilator. Ipratropium and ipratropium/albuterol solutions for nebulization are the only inhaled anticholinergic products that are currently available generically. 11-12 According to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines, inhaled bronchodilators are preferred for the management of COPD. Regular use of long-acting β2-agonists or short- or long-acting anticholinergics improves health status and long-acting anticholinergics reduce the rate of COPD exacerbations and improve the effectiveness of pulmonary rehabilitation. The choice of agent should be based on availability and individual response in terms of symptom relief and side effects. The GOLD guidelines emphasize that the use of long-acting bronchodilators is more effective and convenient than the use of short-acting bronchodilators. 1" @default.
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- W2181877562 title "Therapeutic Class Overview Inhaled Anticholinergics" @default.
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