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- W2182026969 abstract "A large number of design aspects must be considered to engineer tissues for clinical applications. This chapter addresses critical engineering design issues to enable large-scale manufacture and use of a variety of engineered tissues. These challenges include elements of mass transport, biomechanics, biomaterials, and bioelectronics. Important engineering design issues addressed in the chapter include—adaptation of existing bioreactor technology for large-scale cell expansion and three-dimensional tissue production; identification of appropriate techniques for preserving both cells and engineered tissues; development of strategies to promote vascularization of engineered tissues; evaluation of the critical mechanical properties of the tissues that need to be replaced; determination of the minimum values of native tissue mechanical properties required of an engineered tissue; and exploitation of externally applied mechanical stimuli to regulate the development and function of engineered tissues." @default.
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- W2182026969 date "2003-01-01" @default.
- W2182026969 modified "2023-10-17" @default.
- W2182026969 title "Engineering Design Aspects of Tissue Engineering" @default.
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- W2182026969 doi "https://doi.org/10.1016/b978-012484150-5/50009-1" @default.
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