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- W2182046145 abstract "The aim of this stud y was to prepare fast disintegrating tablets of Ziprasidone by using various superdisintegrant. The tablets were prepared usi ng mannitol as diluent and Kyron T - 134 as taste masking agent along with three different levels of superdisintegrant. The superdisi ntegrant used in this study were Crosspovidone, Crosscarmelose sodium and Sodium starch glycolate. The tablets were evaluated for weight variation, hardness, friability, wetting time, water absorption ratio, and disintegration time (DT) and dissolution stu dy. Using the same excipients, the tablets were prepared by direct compression and were evaluated in the similar way. From the results obtained, it can be concluded that the tablet form ulation prepared with 9% Crosspovidone showed Disintegration time of 12 seconds . Also the hardness, friability, dissolution rate (ZD3) were found to be acceptable according to standard limits." @default.
- W2182046145 created "2016-06-24" @default.
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- W2182046145 date "2012-01-01" @default.
- W2182046145 modified "2023-09-27" @default.
- W2182046145 title "DESIGN AND DEVELOPME NT OF FAST DISSOLVIN G TABLETS CONTAINING ZIPRASIDONE BY DIREC T COMPRESSION METHOD" @default.
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