Matches in SemOpenAlex for { <https://semopenalex.org/work/W2182052009> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2182052009 endingPage "85" @default.
- W2182052009 startingPage "79" @default.
- W2182052009 abstract "To investigate the effects of storage temperature on the responsiveness to agonists of human platelets prepared from stored blood, we measured the aggregability and acid-base status of platelets from 96 healthy subjects before and after storage of whole blood at 4 degrees C and room temperature (RT) up to 48 hr. After 24 hr storage at 4 degrees C, there were no significant differences in agonist-induced platelet aggregability, compared to fresh specimens. When blood was kept at RT for 24 hr, all of the platelet samples showed non-responsiveness (< 20% aggregability) to epinephrine and 70% (67/96) revealed impaired responsiveness (20 to 60% aggregability) to adenosine diphosphate (ADP); there were no samples that showed impaired- or non-responsiveness to collagen or ristocetin. Among the 67 samples that showed impaired responsiveness to ADP after RT storage, 62 (93%) exhibited the loss of a secondary wave of aggregation in response to ADP. After storage of blood at RT for 48 hr (pH 6.81 +/- 0.06), mean values of maximal platelet aggregability to epinephrine, ADP, collagen, and ristocetin were 8%, 16%, 19%, and 70%, which were significantly lower than the corresponding mean values after storage of blood at 4 degrees C for 48 hr (pH 7.04 +/- 0.04) (ie, 66%, 69%, 102%, and 91%, p < 0.01). In summary, refrigerated storage of human blood improves the stability of platelet responsiveness to agonists. Storage at RT causes platelet non-responsiveness to epinephrine and disturbs the release reaction of endogenous ADP." @default.
- W2182052009 created "2016-06-24" @default.
- W2182052009 creator A5000670978 @default.
- W2182052009 creator A5020648768 @default.
- W2182052009 date "2003-01-01" @default.
- W2182052009 modified "2023-09-23" @default.
- W2182052009 title "Influence of storage temperature on the responsiveness of human platelets to agonists." @default.
- W2182052009 cites W118128401 @default.
- W2182052009 cites W1602468959 @default.
- W2182052009 cites W1974250473 @default.
- W2182052009 cites W1979626640 @default.
- W2182052009 cites W1984942850 @default.
- W2182052009 cites W2020870305 @default.
- W2182052009 cites W2051202752 @default.
- W2182052009 cites W2058470564 @default.
- W2182052009 cites W2063012449 @default.
- W2182052009 cites W2077486170 @default.
- W2182052009 cites W2083152103 @default.
- W2182052009 cites W2089577000 @default.
- W2182052009 cites W2120549974 @default.
- W2182052009 cites W2316669619 @default.
- W2182052009 cites W2334470538 @default.
- W2182052009 cites W2394794895 @default.
- W2182052009 cites W2412214680 @default.
- W2182052009 cites W2414229891 @default.
- W2182052009 cites W38494535 @default.
- W2182052009 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12661901" @default.
- W2182052009 hasPublicationYear "2003" @default.
- W2182052009 type Work @default.
- W2182052009 sameAs 2182052009 @default.
- W2182052009 citedByCount "4" @default.
- W2182052009 countsByYear W21820520092012 @default.
- W2182052009 countsByYear W21820520092016 @default.
- W2182052009 countsByYear W21820520092018 @default.
- W2182052009 countsByYear W21820520092023 @default.
- W2182052009 crossrefType "journal-article" @default.
- W2182052009 hasAuthorship W2182052009A5000670978 @default.
- W2182052009 hasAuthorship W2182052009A5020648768 @default.
- W2182052009 hasConcept C104317684 @default.
- W2182052009 hasConcept C126322002 @default.
- W2182052009 hasConcept C134018914 @default.
- W2182052009 hasConcept C16613235 @default.
- W2182052009 hasConcept C170493617 @default.
- W2182052009 hasConcept C185592680 @default.
- W2182052009 hasConcept C2775859304 @default.
- W2182052009 hasConcept C2776057759 @default.
- W2182052009 hasConcept C2777399203 @default.
- W2182052009 hasConcept C2778938600 @default.
- W2182052009 hasConcept C2993802102 @default.
- W2182052009 hasConcept C2994266630 @default.
- W2182052009 hasConcept C3020437955 @default.
- W2182052009 hasConcept C42407357 @default.
- W2182052009 hasConcept C512185932 @default.
- W2182052009 hasConcept C55493867 @default.
- W2182052009 hasConcept C71924100 @default.
- W2182052009 hasConcept C89560881 @default.
- W2182052009 hasConceptScore W2182052009C104317684 @default.
- W2182052009 hasConceptScore W2182052009C126322002 @default.
- W2182052009 hasConceptScore W2182052009C134018914 @default.
- W2182052009 hasConceptScore W2182052009C16613235 @default.
- W2182052009 hasConceptScore W2182052009C170493617 @default.
- W2182052009 hasConceptScore W2182052009C185592680 @default.
- W2182052009 hasConceptScore W2182052009C2775859304 @default.
- W2182052009 hasConceptScore W2182052009C2776057759 @default.
- W2182052009 hasConceptScore W2182052009C2777399203 @default.
- W2182052009 hasConceptScore W2182052009C2778938600 @default.
- W2182052009 hasConceptScore W2182052009C2993802102 @default.
- W2182052009 hasConceptScore W2182052009C2994266630 @default.
- W2182052009 hasConceptScore W2182052009C3020437955 @default.
- W2182052009 hasConceptScore W2182052009C42407357 @default.
- W2182052009 hasConceptScore W2182052009C512185932 @default.
- W2182052009 hasConceptScore W2182052009C55493867 @default.
- W2182052009 hasConceptScore W2182052009C71924100 @default.
- W2182052009 hasConceptScore W2182052009C89560881 @default.
- W2182052009 hasIssue "1" @default.
- W2182052009 hasLocation W21820520091 @default.
- W2182052009 hasOpenAccess W2182052009 @default.
- W2182052009 hasPrimaryLocation W21820520091 @default.
- W2182052009 hasRelatedWork W2050235037 @default.
- W2182052009 hasRelatedWork W2065121216 @default.
- W2182052009 hasRelatedWork W2103598224 @default.
- W2182052009 hasRelatedWork W2127981646 @default.
- W2182052009 hasRelatedWork W2134266856 @default.
- W2182052009 hasRelatedWork W2163982080 @default.
- W2182052009 hasRelatedWork W2182052009 @default.
- W2182052009 hasRelatedWork W2403237962 @default.
- W2182052009 hasRelatedWork W2583181154 @default.
- W2182052009 hasRelatedWork W2804680820 @default.
- W2182052009 hasVolume "33" @default.
- W2182052009 isParatext "false" @default.
- W2182052009 isRetracted "false" @default.
- W2182052009 magId "2182052009" @default.
- W2182052009 workType "article" @default.