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- W2182107411 abstract "Background: The present research included a biochemical study for polycystic ovarian syndrome (PCOS) among Iraqi women in Baghdad city .The clinical part included an estimation some of the biochemical parameters and oxidase concentration in overweight and obese (PCOS) groups compared with the control group. Sixty patients with (PCOS),age (19-38) years attended to Kamal AL-Samarai Hospital and AL-Elwia Teaching Hospital for obstetrics and gynecology were included in the present study ,also thirty normal fertile women who served as control group. Blood samples were collected from all individuals from (3-6) days of menstrual cycle.Hormonal assays were done by linked immune-sorbent assay (ELISA), while the ceruloplasmin concentration, copper ,protein and albumin level were measured by using the concentration colorimetric methods (spectrophotometer). The first part of this study included estimation of some hormones: FSH,LH LH:FSH ratio and prolactin were measured in the sera of the control and patients with PCOS . The result indicated a significant (p≤ 0.05) reduction in the sera of FSH was observed seen in PCOS patient compared to control group. Highly significant (p≤ 0.001) increase was noticed in the sera of LH,(LH:FSH) ratio and prolactin in PCOS patients group compared with control group. There was a highly significant (p <0.001) increase in ceruloplasmin concentration [mgml] and copper [µmol/l] and (ceruloplasmin :copper) ratio in PCOS patients compared with the control group. Conclusion: The present study conclude that free radicals have been implicated in the pathogenesis of PCOS ,the current study conclude that the mechanism for high ceruloplasmin and copper is that may be due to might affect their responses to FSH; otherwise, granulosa cells appear to be very accomplished of releasing estrogen in retort to FSH .The findings in this study should be investigated with further trials in order to obtain new insights into PCOS." @default.
- W2182107411 created "2016-06-24" @default.
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- W2182107411 date "2014-01-01" @default.
- W2182107411 modified "2023-09-27" @default.
- W2182107411 title "Study Of Several Biochemical Features in Sera of Patients with Polycystic Ovaries and Compared With the Control Group" @default.
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