FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2182173893> ?p ?o ?g. }

• W2182173893 abstract "The analysis of volatile organic compounds (VOCs) emitted from biological fluids such as blood, urine, breath and faeces, has been receiving more attention from researchers and clinicians due to their contribution to the metabolome and potential use as diagnostic tools in clinical settings. The faecal metabolome represents the final product of a complex interaction involving the gut microbiota and cell metabolism and an accurate measurement of the faecal volatile organic metabolome enables a better understanding of disease-related metabolic pathways and, eventually, identifying potential biomarkers. However, there is a lack of published evidence evaluating the sample preparation steps for faecal metabolome analysis and no well-defined protocol has been established. Consequently, different research groups employ diverse methodologies, which, ultimately, prevent comparison of results between laboratories. We evaluated different aspects of sample preparation when processing murine and human faecal samples through a pipeline involving solid phase micro-extraction (SPME) coupled to gas chromatography-mass spectrometry (GC-MS). We identified the sample volume, the SPME fibre coating, the extraction conditions and the vial volume that produce the most accurate and reproducible results. Finally, we propose an optimized method for the direct SPME-GC-MS analysis of VOCs in murine and human faecal samples. To the best of our knowledge, this is the first work evaluating different aspects of sample preparation for direct SPME-GC-MS analysis of VOCs and the first method proposed for the analysis of murine and human faecal samples. In addition, our proposed method can be coupled to the Automated Mass Spectral Deconvolution and Identification System (AMDIS) and the R software package, Metab, in order to produce results in a reliable and high-throughput manner." @default.
• W2182173893 created "2016-06-24" @default.
• W2182173893 creator A5022616845 @default.
• W2182173893 date "2014-01-01" @default.
• W2182173893 modified "2023-09-26" @default.
• W2182173893 title "Optimisation of Sample Preparation for Direct SPME-GC-MS Analysis of Murine and Human Faecal Volatile Organic Compounds for Metabolomic Studies" @default.
• W2182173893 cites W118065705 @default.
• W2182173893 cites W1500730898 @default.
• W2182173893 cites W1569758561 @default.
• W2182173893 cites W1619726012 @default.
• W2182173893 cites W1964351185 @default.
• W2182173893 cites W1967281759 @default.
• W2182173893 cites W1969714116 @default.
• W2182173893 cites W1969761972 @default.
• W2182173893 cites W1990032588 @default.
• W2182173893 cites W2010622747 @default.
• W2182173893 cites W2018391955 @default.
• W2182173893 cites W2038775271 @default.
• W2182173893 cites W2041341409 @default.
• W2182173893 cites W2054204279 @default.
• W2182173893 cites W2055773789 @default.
• W2182173893 cites W2063139643 @default.
• W2182173893 cites W2066328597 @default.
• W2182173893 cites W2075081792 @default.
• W2182173893 cites W2076461297 @default.
• W2182173893 cites W2079499441 @default.
• W2182173893 cites W2081164775 @default.
• W2182173893 cites W2100316629 @default.
• W2182173893 cites W2112324327 @default.
• W2182173893 cites W2135572109 @default.
• W2182173893 cites W2140571939 @default.
• W2182173893 cites W2142338182 @default.
• W2182173893 cites W2339886882 @default.
• W2182173893 cites W80017870 @default.
• W2182173893 doi "https://doi.org/10.4172/2155-9872.1000184" @default.
• W2182173893 hasPublicationYear "2014" @default.
• W2182173893 type Work @default.
• W2182173893 sameAs 2182173893 @default.
• W2182173893 citedByCount "21" @default.
• W2182173893 countsByYear W21821738932015 @default.
• W2182173893 countsByYear W21821738932016 @default.
• W2182173893 countsByYear W21821738932017 @default.
• W2182173893 countsByYear W21821738932018 @default.
• W2182173893 countsByYear W21821738932019 @default.
• W2182173893 countsByYear W21821738932020 @default.
• W2182173893 countsByYear W21821738932021 @default.
• W2182173893 crossrefType "journal-article" @default.
• W2182173893 hasAuthorship W2182173893A5022616845 @default.
• W2182173893 hasBestOaLocation W21821738931 @default.
• W2182173893 hasConcept C123460561 @default.
• W2182173893 hasConcept C135870905 @default.
• W2182173893 hasConcept C162356407 @default.
• W2182173893 hasConcept C178790620 @default.
• W2182173893 hasConcept C185592680 @default.
• W2182173893 hasConcept C205345274 @default.
• W2182173893 hasConcept C21565614 @default.
• W2182173893 hasConcept C2778150766 @default.
• W2182173893 hasConcept C2778533135 @default.
• W2182173893 hasConcept C2778576202 @default.
• W2182173893 hasConcept C2780026642 @default.
• W2182173893 hasConcept C43617362 @default.
• W2182173893 hasConcept C55493867 @default.
• W2182173893 hasConcept C93353639 @default.
• W2182173893 hasConceptScore W2182173893C123460561 @default.
• W2182173893 hasConceptScore W2182173893C135870905 @default.
• W2182173893 hasConceptScore W2182173893C162356407 @default.
• W2182173893 hasConceptScore W2182173893C178790620 @default.
• W2182173893 hasConceptScore W2182173893C185592680 @default.
• W2182173893 hasConceptScore W2182173893C205345274 @default.
• W2182173893 hasConceptScore W2182173893C21565614 @default.
• W2182173893 hasConceptScore W2182173893C2778150766 @default.
• W2182173893 hasConceptScore W2182173893C2778533135 @default.
• W2182173893 hasConceptScore W2182173893C2778576202 @default.
• W2182173893 hasConceptScore W2182173893C2780026642 @default.
• W2182173893 hasConceptScore W2182173893C43617362 @default.
• W2182173893 hasConceptScore W2182173893C55493867 @default.
• W2182173893 hasConceptScore W2182173893C93353639 @default.
• W2182173893 hasIssue "2" @default.
• W2182173893 hasLocation W21821738931 @default.
• W2182173893 hasOpenAccess W2182173893 @default.
• W2182173893 hasPrimaryLocation W21821738931 @default.
• W2182173893 hasRelatedWork W177454211 @default.
• W2182173893 hasRelatedWork W1969714116 @default.
• W2182173893 hasRelatedWork W2004454890 @default.
• W2182173893 hasRelatedWork W2037157845 @default.
• W2182173893 hasRelatedWork W2078279115 @default.
• W2182173893 hasRelatedWork W2080276667 @default.
• W2182173893 hasRelatedWork W2182173893 @default.
• W2182173893 hasRelatedWork W2603425443 @default.
• W2182173893 hasRelatedWork W2753537341 @default.
• W2182173893 hasRelatedWork W2966649258 @default.
• W2182173893 hasVolume "5" @default.
• W2182173893 isParatext "false" @default.
• W2182173893 isRetracted "false" @default.
• W2182173893 magId "2182173893" @default.
• W2182173893 workType "article" @default.