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- W2182180634 abstract "A crosssectional study was carried out for serological detection and liver functions of pediatric visceral leishmaniasis (VL) in Baghdad hospitals during the period from July 2013 to September 2014. Results were showed that the distribution of leishmaniasis according to sex which diagnosed with IFAT and rk39 techniques revealed there was no significant difference (p 0.05). From total of one hundred and seventy eight clinical suspected cases of Kala-azar who had studied the majority of cases 23 patients (46.0%) below 4 years old, so it is proved that the majority of visceral leishmaniasis among children. Analysis of total serum protein level of patients mean were 7.475 g/L (mean ± SD0.626) as compared to controls mean (7.292 g/L) (mean ± SD 0.705), and there were significantly increase of mean serum albumin level, while globulin was observed in the patients 3.225 g/L (mean ± SD 0.639) and 4.252 g/L (mean ± SD0.738) in compared to healthy control (4.384 g/L mean ± SD0.549 and 2.902 g/Lmean ± SD0.493), respectively. Albumin/globulin ratio was highly significant (P<0.01) in VL patients as compared to healthy control groups, so its mean value was in apparently healthy control 1.561 (mean ± SD0.379), while in leishmaniasis patients 0.793 (mean ± SD0.251). Determination of mean total serum bilirubin, mean serum direct bilirubin and mean serum indirect bilirubin of the study were showed there were no significant effects through leishmaniasis cases (P 0.05), which was 0.979 mg/dl, 0.533 mg/dl and 0.624 mg/dl, respectively. The biochemical tests includes assays of alanine 2-oxoglutarate aminotransferase (ALT), aspartate: 2oxoglutarate aminotransferase (AST) and alkaline phosphatase were estimated that revealed higher significant P<0.01 value in leishmaniasis patients than healthy controls, with mean value of 58.43 (IU/L), 87.374 (IU/L) and 238.14 (IU/L), respectively. The study indicated that serological tests and detection of liver enzymatic functions results having better estimation in diagnosis of VL patients. K e y w o r d s" @default.
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- W2182180634 date "2015-01-01" @default.
- W2182180634 modified "2023-09-26" @default.
- W2182180634 title "Serological detection and liver functions of pediatric visceral leishmaniasis in Baghdad hospitals" @default.
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