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- W2182197920 abstract "Changes in the levels of three structurally and functionally different important thermoprotectant molecules, namely small heat shock proteins (sHsps), trehalose, and lipids, have been investigated upon heat shock in Schizosaccharomyces pombe. Both α-crystallin-type sHsps (Hsp15.8 and Hsp16) were induced after prolonged high-temperature treatment but with different kinetic profiles. The shsp null mutants display a weak, but significant, heat sensitivity indicating their importance in the thermal stress management. The heat induction of sHsps is different in wild type and in highly heat-sensitive trehalose-deficient (tps1Δ) cells; however, trehalose level did not show significant alteration in shsp mutants. The altered timing of trehalose accumulation and induction of sHsps suggest that the disaccharide might provide protection at the early stage of the heat stress while elevated amount of sHsps are required at the later phase. The cellular lipid compositions of two different temperature-adapted wild-type S. pombe cells are also altered according to the rule of homeoviscous adaptation, indicating their crucial role in adapting to the environmental temperature changes. Both Hsp15.8 and Hsp16 are able to bind to different lipids isolated from S. pombe, whose interaction might provide a powerful protection against heat-induced damages of the membranes. Our data suggest that all the three investigated thermoprotectant macromolecules play a pivotal role during the thermal stress management in the fission yeast." @default.
- W2182197920 created "2016-06-24" @default.
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- W2182197920 date "2015-12-02" @default.
- W2182197920 modified "2023-10-14" @default.
- W2182197920 title "Involvement of small heat shock proteins, trehalose, and lipids in the thermal stress management in Schizosaccharomyces pombe" @default.
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- W2182197920 cites W1605141624 @default.
- W2182197920 cites W1677466026 @default.
- W2182197920 cites W1775749144 @default.
- W2182197920 cites W1821834644 @default.
- W2182197920 cites W1966916940 @default.
- W2182197920 cites W1967025651 @default.
- W2182197920 cites W1967622387 @default.
- W2182197920 cites W1970216050 @default.
- W2182197920 cites W1970243665 @default.
- W2182197920 cites W1970946311 @default.
- W2182197920 cites W1975425948 @default.
- W2182197920 cites W1980881084 @default.
- W2182197920 cites W1981924974 @default.
- W2182197920 cites W1985530849 @default.
- W2182197920 cites W1990647376 @default.
- W2182197920 cites W1996968937 @default.
- W2182197920 cites W1997243880 @default.
- W2182197920 cites W2004854794 @default.
- W2182197920 cites W2010335064 @default.
- W2182197920 cites W2011563930 @default.
- W2182197920 cites W2013801020 @default.
- W2182197920 cites W2024082726 @default.
- W2182197920 cites W2024127505 @default.
- W2182197920 cites W2025868611 @default.
- W2182197920 cites W2027174470 @default.
- W2182197920 cites W2032476635 @default.
- W2182197920 cites W2035228518 @default.
- W2182197920 cites W2037623924 @default.
- W2182197920 cites W2038579824 @default.
- W2182197920 cites W2038862228 @default.
- W2182197920 cites W2039959 @default.
- W2182197920 cites W2043831708 @default.
- W2182197920 cites W2045913841 @default.
- W2182197920 cites W2046201295 @default.
- W2182197920 cites W2051642123 @default.
- W2182197920 cites W2053300791 @default.
- W2182197920 cites W2055085279 @default.
- W2182197920 cites W2056459445 @default.
- W2182197920 cites W2056788983 @default.
- W2182197920 cites W2061020991 @default.
- W2182197920 cites W2061141737 @default.
- W2182197920 cites W2062539976 @default.
- W2182197920 cites W2068511285 @default.
- W2182197920 cites W2068625350 @default.
- W2182197920 cites W2079121387 @default.
- W2182197920 cites W2080365239 @default.
- W2182197920 cites W2089643766 @default.
- W2182197920 cites W2095666570 @default.
- W2182197920 cites W2102614052 @default.
- W2182197920 cites W2102747561 @default.
- W2182197920 cites W2108675105 @default.
- W2182197920 cites W2112295687 @default.
- W2182197920 cites W2116084873 @default.
- W2182197920 cites W2119269332 @default.
- W2182197920 cites W2124610014 @default.
- W2182197920 cites W2125646034 @default.
- W2182197920 cites W2126834219 @default.
- W2182197920 cites W2127957413 @default.
- W2182197920 cites W2128067577 @default.
- W2182197920 cites W2131176478 @default.
- W2182197920 cites W2133714596 @default.
- W2182197920 cites W2134809769 @default.
- W2182197920 cites W2138305150 @default.
- W2182197920 cites W2142132211 @default.
- W2182197920 cites W2156350829 @default.
- W2182197920 cites W2164858228 @default.
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- W2182197920 doi "https://doi.org/10.1007/s12192-015-0662-4" @default.
- W2182197920 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4786532" @default.
- W2182197920 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26631139" @default.
- W2182197920 hasPublicationYear "2015" @default.
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