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- W2182243366 abstract "Our current understanding of pain perception is a synthesis of neurophysiology, neuropharmacology, and neuroanatomy. Neurophysiologic concepts developed in the late 19th century and refined over the last 20 years have provided a strong conceptual framework through which rigorous scientific methodology has been applied to analyze how our central nervous system receives and analyzes information regarding pain. Moreover, neuropharmacologic and neuroanatomic data gathered over the last several decades has extended our knowledge of somatosensory information processing to relatively sophisticated levels regarding neurochemical events within specific neuroanatomic structures. The goal of this chapter is to review these three fields as they relate to nociceptive (i.e., pain) information processing, and to integrate them into a framework that will enable a logical approach to the analysis and treatment of pain. This will be achieved by reviewing the major neurophysiologic theories of pain perception and examining how current neurophysiologie and neuroanatomic data support or detract from these theories. We will then review the neuroanatomy relevant to pain perception, and, where appropriate, discuss the neurochemistry that appears relevant to nociception. In doing this, what emerges is a circuit involved in the perception and modulation of pain that can be briefly described and easily comprehended." @default.
- W2182243366 created "2016-06-24" @default.
- W2182243366 creator A5071664246 @default.
- W2182243366 date "1989-01-01" @default.
- W2182243366 modified "2023-10-18" @default.
- W2182243366 title "Physiology, Anatomy, and Pharmacology of Pain Perception" @default.
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- W2182243366 doi "https://doi.org/10.1007/978-1-4613-8868-5_2" @default.
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