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W2182276577 abstract "Several pharmaceutical companies are currently developing bi-layer tablets, for a variety of reasons: patent extension, therapeutic, marketing to name a few. To reduce capital investment, quite often existing but modified tablet presses are used to develop and produce such tablets. Using a modified tablet press may therefore not be your best approach in producing a quality bi-layer tablet under GMP-conditions, especially when high production output is required. Over the past 30 years as the expense and complications involved in marketing new drug entities have increased, with concomitant recognition of the therapeutic advantages of controlled drug delivery, greater attention has been focused on development of sustained or controlled release drug delivery systems. Bilayer tablet is new era for the successful development of controlled release formulation along with various features to provide a way of successful drug delivery system. Keywords Bilayer tablet, Layer separation, Insufficient hardness, Individual layer weight control" @default.
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W2182276577 date "2017-02-28" @default.
W2182276577 modified "2023-09-24" @default.
W2182276577 title "REVIEW: BILAYER TABLET AND EVALUATION" @default.
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