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- W2182294311 abstract "To investigate the serum expressions of chemokines CCL2 and CCL3 in patients with rheumatoid arthritis (RA) who were treated with recombinant human interleukin 1 (IL-1) receptor antagonist (IL-1Ra).Serum CCL2 and CCL3 were determined using an enzyme-linked immunosorbent assay in 54 active RA patients before and after treatment with IL-1Ra or a placebo, as well as 36 healthy controls.Compared with the healthy controls, all the 54 RA patients exhibited higher serum CCL2 and CCL3 before and after treatment (p < 0.05). However, patients who had a good response to IL-1Ra treatment had significantly lower mean changes in the serum CCL2 and CCL3 levels from baseline to the last injection than IL-1Ra non-responders (p < 0.01).CCL2 and CCL3 may be useful efficacy markers of IL-1Ra treatment." @default.
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- W2182294311 date "2014-01-01" @default.
- W2182294311 modified "2023-09-28" @default.
- W2182294311 title "Clinical immunology Recombinant human interleukin receptor antagonist influences serum chemokines in patients with rheumatoid arthritis" @default.
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- W2182294311 doi "https://doi.org/10.5114/ceji.2014.43717" @default.
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