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- W2182325700 abstract "Summary The present work was carried out to study the effect of Coleus aromaticus leaves on blood glucose and antioxidant enzymes levels in alloxan rendered diabetic rats. Alloxan (150 mg/kg body wt. i.p.) induced diabetic rats were treated with aqueous and ethanolic extracts of Coleus aromaticus at dose of 200 mg/kg twice daily 12 hours cycle (8:00 am and 8:00 pm) for 8 weeks. The concentration of glucose in the blood and antioxidant enzymes levels viz. superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPX) and malondialdehyde (MDA) in liver homogenate were measured. Aqueous and ethanolic extract of Coleus aromaticus significantly (p<0.01 and p<0.001) lowered the alloxan mediated hyperglycemia . The activity of antioxidant enzymes such as SOD, CAT and GPxase were found to be increased in the liver homogenate of diabetic animals treated with both the extracts of Coleus aromaticus . Test extracts also produced significant decrease in MDA level compered to diabetic control. This confirms the antihyperglycaemic and antioxidant activity of Coleus aromaticus in alloxan induced diabetic rats. Among the tested extracts, ethanolic extract of Coleus aromaticus leaves was found to be having potent antihyperglycemic activity than the aqueous extract." @default.
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- W2182325700 date "2009-01-01" @default.
- W2182325700 modified "2023-09-24" @default.
- W2182325700 title "ATIDIABETIC AD ATIOXIDAT POTETIAL OF COLEUS AROMATICUS LEAF EXTRACTS IALLOXAIDUCED DIABETIC RATS" @default.
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