FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2182479498> ?p ?o ?g. }

• W2182479498 endingPage "8" @default.
• W2182479498 startingPage "275" @default.
• W2182479498 abstract "Androgen receptors play critical roles in the development of primary as well as advanced hormone-refractory prostate cancers. Since the growth of prostate cancer is androgen-sensitive, metastatic disease has been treated by hormonal therapy in the form of androgen ablation. Prostate cancer cells rely on androgen receptor (AR) for proliferation and survival.To evaluate the prognostic significance of androgen receptor polymorphism in patients under hormonal therapy in any form.Complete follow up data were available for 87 patients out of 130 patients enrolled for study. DNA was extracted from blood samples using salting out method and then subjected to PCR Genscan for CAG and GGN genotyping. The mean follow up was 10.12+/-8.83 months.Out of 87 patients, 64 experienced clinical as well as biochemical recurrence. The overall hormone refractory rates were 73.4% after one year. We observed a significant shorter median CAG repeats in HRPC patients (20 vs 22). The hazard ratio for HRPCs with the < or =20 CAG repeat genotype was 0.602 (0.33-1.08, p=0.09). Kaplan-Meier analysis showed that HRPC rates were not significantly associated with CAG repeat (p=0.06) but a trend was observed with short CAG repeats. No significant association was observed with AR-GGN repeats.A trend for association of AR-CAG repeats with HRPC patients in north Indian population was observed, suggesting this to be a prognostic factor for determining the therapeutic regimen." @default.
• W2182479498 created "2016-06-24" @default.
• W2182479498 creator A5014548378 @default.
• W2182479498 creator A5049932826 @default.
• W2182479498 creator A5069150930 @default.
• W2182479498 date "2007-08-19" @default.
• W2182479498 modified "2023-09-23" @default.
• W2182479498 title "Role of an androgen receptor gene polymorphism in development of hormone refractory prostate cancer in Indian population." @default.
• W2182479498 cites W1531829664 @default.
• W2182479498 cites W1533310838 @default.
• W2182479498 cites W1550437130 @default.
• W2182479498 cites W1753444892 @default.
• W2182479498 cites W1976706733 @default.
• W2182479498 cites W1988679331 @default.
• W2182479498 cites W2012639187 @default.
• W2182479498 cites W2021508919 @default.
• W2182479498 cites W2023654765 @default.
• W2182479498 cites W2032432671 @default.
• W2182479498 cites W2054045654 @default.
• W2182479498 cites W2060559284 @default.
• W2182479498 cites W2061623465 @default.
• W2182479498 cites W2062646100 @default.
• W2182479498 cites W2085194185 @default.
• W2182479498 cites W2099594535 @default.
• W2182479498 cites W2103576304 @default.
• W2182479498 cites W2118094114 @default.
• W2182479498 cites W2144616720 @default.
• W2182479498 cites W2155679349 @default.
• W2182479498 cites W575389344 @default.
• W2182479498 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17696745" @default.
• W2182479498 hasPublicationYear "2007" @default.
• W2182479498 type Work @default.
• W2182479498 sameAs 2182479498 @default.
• W2182479498 citedByCount "4" @default.
• W2182479498 countsByYear W21824794982013 @default.
• W2182479498 countsByYear W21824794982015 @default.
• W2182479498 countsByYear W21824794982016 @default.
• W2182479498 countsByYear W21824794982018 @default.
• W2182479498 crossrefType "journal-article" @default.
• W2182479498 hasAuthorship W2182479498A5014548378 @default.
• W2182479498 hasAuthorship W2182479498A5049932826 @default.
• W2182479498 hasAuthorship W2182479498A5069150930 @default.
• W2182479498 hasConcept C104317684 @default.
• W2182479498 hasConcept C121608353 @default.
• W2182479498 hasConcept C126322002 @default.
• W2182479498 hasConcept C134018914 @default.
• W2182479498 hasConcept C135763542 @default.
• W2182479498 hasConcept C143998085 @default.
• W2182479498 hasConcept C207103383 @default.
• W2182479498 hasConcept C2776235491 @default.
• W2182479498 hasConcept C2777911890 @default.
• W2182479498 hasConcept C2778311097 @default.
• W2182479498 hasConcept C2780192828 @default.
• W2182479498 hasConcept C2780275930 @default.
• W2182479498 hasConcept C2908647359 @default.
• W2182479498 hasConcept C31467283 @default.
• W2182479498 hasConcept C44249647 @default.
• W2182479498 hasConcept C530470458 @default.
• W2182479498 hasConcept C54355233 @default.
• W2182479498 hasConcept C61367390 @default.
• W2182479498 hasConcept C71315377 @default.
• W2182479498 hasConcept C71924100 @default.
• W2182479498 hasConcept C86803240 @default.
• W2182479498 hasConcept C99454951 @default.
• W2182479498 hasConceptScore W2182479498C104317684 @default.
• W2182479498 hasConceptScore W2182479498C121608353 @default.
• W2182479498 hasConceptScore W2182479498C126322002 @default.
• W2182479498 hasConceptScore W2182479498C134018914 @default.
• W2182479498 hasConceptScore W2182479498C135763542 @default.
• W2182479498 hasConceptScore W2182479498C143998085 @default.
• W2182479498 hasConceptScore W2182479498C207103383 @default.
• W2182479498 hasConceptScore W2182479498C2776235491 @default.
• W2182479498 hasConceptScore W2182479498C2777911890 @default.
• W2182479498 hasConceptScore W2182479498C2778311097 @default.
• W2182479498 hasConceptScore W2182479498C2780192828 @default.
• W2182479498 hasConceptScore W2182479498C2780275930 @default.
• W2182479498 hasConceptScore W2182479498C2908647359 @default.
• W2182479498 hasConceptScore W2182479498C31467283 @default.
• W2182479498 hasConceptScore W2182479498C44249647 @default.
• W2182479498 hasConceptScore W2182479498C530470458 @default.
• W2182479498 hasConceptScore W2182479498C54355233 @default.
• W2182479498 hasConceptScore W2182479498C61367390 @default.
• W2182479498 hasConceptScore W2182479498C71315377 @default.
• W2182479498 hasConceptScore W2182479498C71924100 @default.
• W2182479498 hasConceptScore W2182479498C86803240 @default.
• W2182479498 hasConceptScore W2182479498C99454951 @default.
• W2182479498 hasIssue "2" @default.
• W2182479498 hasLocation W21824794981 @default.
• W2182479498 hasOpenAccess W2182479498 @default.
• W2182479498 hasPrimaryLocation W21824794981 @default.
• W2182479498 hasRelatedWork W2004261902 @default.
• W2182479498 hasRelatedWork W2041719533 @default.
• W2182479498 hasRelatedWork W2062439823 @default.
• W2182479498 hasRelatedWork W2117213328 @default.
• W2182479498 hasRelatedWork W2806585884 @default.
• W2182479498 hasRelatedWork W2953834125 @default.
• W2182479498 hasRelatedWork W3049021892 @default.
• W2182479498 hasRelatedWork W3129730550 @default.

• next