FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2182661750> ?p ?o ?g. }

• W2182661750 endingPage "110" @default.
• W2182661750 startingPage "102" @default.
• W2182661750 abstract "Objective(s) Physiological changes in the body may be utilized as potential triggers for controlled drug delivery. Based on these mechanisms, stimulus–responsive drug delivery has been developed. Materials and Methods In this study, a kind of poly (N-isopropylacrylamide-acrylamide) membrane was prepared by radical copolymerization. Changes in swelling ratios and diameters of the membrane were investigated in terms of temperature. On-off regulation of drug permeation through the membrane was then studied at temperatures below and above the phase transition temperature of the membrane. Two drugs, vitamin B12 and acetaminophen were chosen as models of high and low molecular weights here, respectively. Results It was indicated that at temperatures below the phase transition temperature of the membrane, copolymer was in a swollen state. Above the phase transition temperature, water was partially expelled from the functional groups of the copolymer. Permeation of high molecular weight drug models such as vitamin B12 was shown to be much more distinct at temperatures below the phase transition temperature when the copolymer was in a swollen state. At higher temperatures when the copolymer was shrunken, drug permeation through the membrane was substantially decreased. However for acetaminophen, such a big change in drug permeation around the phase transition temperature of the membrane was not observed. Conclusion According to the pore mechanism of drug transport through hydrogels, permeability of solutes decreased with increasing molecular size. As a result, the relative permeability, around the phase transition temperature of the copolymer, was higher for solutes of high molecular weight." @default.
• W2182661750 created "2016-06-24" @default.
• W2182661750 creator A5044506340 @default.
• W2182661750 creator A5047476297 @default.
• W2182661750 creator A5063540843 @default.
• W2182661750 creator A5077206481 @default.
• W2182661750 creator A5080076536 @default.
• W2182661750 date "2010-07-01" @default.
• W2182661750 modified "2023-09-26" @default.
• W2182661750 title "Preparation and Investigation of Poly (N-isopropylacrylamide-acrylamide) Membranes in Temperature Responsive Drug Delivery" @default.
• W2182661750 cites W1600269130 @default.
• W2182661750 cites W1964514479 @default.
• W2182661750 cites W1971178120 @default.
• W2182661750 cites W1976996871 @default.
• W2182661750 cites W1983193280 @default.
• W2182661750 cites W1993023194 @default.
• W2182661750 cites W2004616899 @default.
• W2182661750 cites W2012320985 @default.
• W2182661750 cites W2012468775 @default.
• W2182661750 cites W2013631337 @default.
• W2182661750 cites W2025420010 @default.
• W2182661750 cites W2026993603 @default.
• W2182661750 cites W2051419872 @default.
• W2182661750 cites W2051830158 @default.
• W2182661750 cites W2077275571 @default.
• W2182661750 cites W2107092681 @default.
• W2182661750 cites W2117995992 @default.
• W2182661750 cites W2242647871 @default.
• W2182661750 cites W2253596446 @default.
• W2182661750 cites W2267233124 @default.
• W2182661750 cites W2279130280 @default.
• W2182661750 doi "https://doi.org/10.22038/ijbms.2010.5095" @default.
• W2182661750 hasPublicationYear "2010" @default.
• W2182661750 type Work @default.
• W2182661750 sameAs 2182661750 @default.
• W2182661750 citedByCount "3" @default.
• W2182661750 countsByYear W21826617502013 @default.
• W2182661750 countsByYear W21826617502015 @default.
• W2182661750 countsByYear W21826617502018 @default.
• W2182661750 crossrefType "journal-article" @default.
• W2182661750 hasAuthorship W2182661750A5044506340 @default.
• W2182661750 hasAuthorship W2182661750A5047476297 @default.
• W2182661750 hasAuthorship W2182661750A5063540843 @default.
• W2182661750 hasAuthorship W2182661750A5077206481 @default.
• W2182661750 hasAuthorship W2182661750A5080076536 @default.
• W2182661750 hasConcept C121332964 @default.
• W2182661750 hasConcept C127413603 @default.
• W2182661750 hasConcept C149288129 @default.
• W2182661750 hasConcept C15920480 @default.
• W2182661750 hasConcept C178790620 @default.
• W2182661750 hasConcept C185592680 @default.
• W2182661750 hasConcept C188027245 @default.
• W2182661750 hasConcept C188109995 @default.
• W2182661750 hasConcept C2776892847 @default.
• W2182661750 hasConcept C2778540859 @default.
• W2182661750 hasConcept C2779402116 @default.
• W2182661750 hasConcept C2779820397 @default.
• W2182661750 hasConcept C41625074 @default.
• W2182661750 hasConcept C42360764 @default.
• W2182661750 hasConcept C43617362 @default.
• W2182661750 hasConcept C50670333 @default.
• W2182661750 hasConcept C521977710 @default.
• W2182661750 hasConcept C55493867 @default.
• W2182661750 hasConcept C97355855 @default.
• W2182661750 hasConceptScore W2182661750C121332964 @default.
• W2182661750 hasConceptScore W2182661750C127413603 @default.
• W2182661750 hasConceptScore W2182661750C149288129 @default.
• W2182661750 hasConceptScore W2182661750C15920480 @default.
• W2182661750 hasConceptScore W2182661750C178790620 @default.
• W2182661750 hasConceptScore W2182661750C185592680 @default.
• W2182661750 hasConceptScore W2182661750C188027245 @default.
• W2182661750 hasConceptScore W2182661750C188109995 @default.
• W2182661750 hasConceptScore W2182661750C2776892847 @default.
• W2182661750 hasConceptScore W2182661750C2778540859 @default.
• W2182661750 hasConceptScore W2182661750C2779402116 @default.
• W2182661750 hasConceptScore W2182661750C2779820397 @default.
• W2182661750 hasConceptScore W2182661750C41625074 @default.
• W2182661750 hasConceptScore W2182661750C42360764 @default.
• W2182661750 hasConceptScore W2182661750C43617362 @default.
• W2182661750 hasConceptScore W2182661750C50670333 @default.
• W2182661750 hasConceptScore W2182661750C521977710 @default.
• W2182661750 hasConceptScore W2182661750C55493867 @default.
• W2182661750 hasConceptScore W2182661750C97355855 @default.
• W2182661750 hasIssue "346" @default.
• W2182661750 hasLocation W21826617501 @default.
• W2182661750 hasOpenAccess W2182661750 @default.
• W2182661750 hasPrimaryLocation W21826617501 @default.
• W2182661750 hasRelatedWork W1976215548 @default.
• W2182661750 hasRelatedWork W1994840182 @default.
• W2182661750 hasRelatedWork W2002503814 @default.
• W2182661750 hasRelatedWork W2008124244 @default.
• W2182661750 hasRelatedWork W2025850420 @default.
• W2182661750 hasRelatedWork W2026207135 @default.
• W2182661750 hasRelatedWork W2030141189 @default.
• W2182661750 hasRelatedWork W2031934042 @default.
• W2182661750 hasRelatedWork W2042463429 @default.
• W2182661750 hasRelatedWork W2087211179 @default.
• W2182661750 hasRelatedWork W2092222250 @default.

• next