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- W2182731215 abstract "The investigation on general and genetic toxicity of Bakhour smoke inhalation in Swiss albino mice was undertaken in view of the literature reports on adverse effects of incense smoke and a paucity of literature on the general and genetic toxicity of Bakhour. The present study was conducted on both the sexes of Swiss albino mice. Treatment included exposure to a dose of 115 gram Bakhour burning smoke for a period of 2 hour, daily for 7 days. The observations on toxicity involved; behavioral changes (autonomic responses, motor activity and central nervous system), effect on body and organ weight and rate of mortality. Micronucleus test was used to determine the genetic toxicity. The different parameters studied were subjected to statistica l analysis with one way ANOVA and Post hoc Tukey-Kramer multiple comparison test. The sub-acute treatment with Bakhour smoke failed to induce any significant changes in the symptoms of general toxicity as compared to the control. The animals remained calm during the treatment. There was moderate increase in respiration and mild increase in pilo erection and allergic symptoms. There was no mortality and effect on body weight. But weight of lungs altered significantly. The treatment failed to affect the frequency of micronucleate d- polychromatic erythrocytes (PCE) and the ratio of PCE/normochromatic erythrocytes (NCE). The results of this preliminary report showed that Bakhour smoke is non- toxic. Nevertheless, there is a need for more extensive studies that include analyzing composition of Bakhour smoke, comparing the smoke of Bakhour with that of the smoke from other sources, in addition to extensive studies on chronic toxicity." @default.
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- W2182731215 date "2013-01-01" @default.
- W2182731215 modified "2023-09-26" @default.
- W2182731215 title "Preliminary Studies on General and Genetic Toxicity of Incense (Bakhour) Inhalation in Swiss Albino Mice" @default.
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