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• W2183119300 abstract "Background: Strict carnivores such as the mink are considered to have limited ability to adapt protein metabolism to varied protein provision. However, some metabolic adaptation has previously been observed in lactating minks. This was further investigated in this study. Methods: quantitative metabolism (balance and respiration experiments), kit growth, and plasma amino acids concentrations and liver mass in lactating dams, as well as relative mRNA abundance of some key hepatic enzymes (qPCR) after weaning of the kits, were studied. Lactating mink dams were assigned to one of three diets (high- (HP: 60% of metabolisable energy (ME)), medium- (MP: 45% of ME), or low- (LP: 30% of ME) protein), from parturition until ten weeks post partum. Tissue samples were collected 2, 3, 4 and 10 weeks post partum. Results: Diet did not affect (P > 0.05) heat production. The protein provision was clearly reflected in the protein oxidation, and dams fed the HP diet had a higher N excretion, larger liver mass, and tended to have higher weight loss and lower estimated milk production through the four first lactation weeks. Plasma amino acid profiles and liver weights 10 weeks post partum were generally unaffected by dietary protein provision. Besides, the diets did not affect relative abundance of the studied mRNAs in hepatic tissue. Conclusion: Metabolic adaptation in lactating mink dams seems limited mainly to adjustment of liver mass, but that the relative abundance of mRNA for key gluconeogenic enzymes is unaffected by diet indicates that these animals' capacity to regulate enzyme activity is limited." @default.
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• W2183119300 date "2012-01-01" @default.
• W2183119300 modified "2023-09-26" @default.
• W2183119300 title "Metabolic adaptation to different protein supply in mink (Neovison vison)" @default.
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