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- W2183140554 abstract "Several lymphoma T cell lines differ in membrane superficial markers and do not respond to the same drugs and compounds. Tilia x viridis (Bayer) Simonk nothosubspecie moltkei (Dippel) Xifreda is a plant widely distributed in Argentina. The aim of this work was to study comparatively the effects of dichloromethane extract and isolated compounds on BW 5147 and on another T lymphoma cell line EL-4, evaluating principally proliferation and viability. On BW 5147 cells, dichloromethane extract exerted antiproliferative action, presented cytostatic effect at low concentrations and cytotoxic action at high concentrations. Monoterpenes exerted antiproliferative action being the most potent limonene; low concentrations of them were cytostatic and high concentrations were cytotoxic. On EL-4 lymphoma, dichloromethane extract and monoterpenes exerted proliferative action, and none of them affected cell viability. It is extremely important to note that depending on tumor cell type the same extract or compounds can elicit different actions." @default.
- W2183140554 created "2016-06-24" @default.
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- W2183140554 date "2010-01-01" @default.
- W2183140554 modified "2023-09-26" @default.
- W2183140554 title "Comparative study of Tilia x viridis extract and isolated compounds on the proliferation of two lymphoma cell lines." @default.
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