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• W2183204080 abstract "Alpha-lipoic acid and panax ginseng are widely used as natural dietary supplements because these compounds exert antihypercholesterolemic effects, not only in experimental animals but also in humans. The current study aimed to evaluate the effects of supplementation with lipoic acid (LA) and panax ginseng on the lipid profile of newly investigated hypercholesterolemic patients. Forty adult newly investigated hypercholesterolemic patients, ranging in age from 40 to 60 years,were advised to perform exercise one hour daily and to consume low fat diet and divided in to three groups as follows; Group 1 (healthy individuals served as normal control), Group 2 receiving 600 mg alpha-lipoic acid twice daily for two months and Group 3 receiving 100 mg ginseng twice daily for two months. Then plasma lipid profile was determined. Administration of alpha- lipoic acid for one month showed a significant reduction in LDL only, while after two months both low-density lipoprotein and total cholesterol were significantly reduced as compared to hypercholesterolemic patients, on the other hand administration of panax ginseng for one or two months showed a significant reduction in low- density lipoprotein, total cholesterol, LDL/HDL and CHOL/HDL ratios as compared to hypercholesterolemic patients. Although this study showed an improvement in low-density lipoprotein and total cholesterol in newly investigated hypercholesterolemic patients after alpha-lipoic acid administration for two months, the improvement effects of panax ginseng was shown to be more effective in reducing low-density lipoprotein, total cholesterol, LDL/HDL and cholesterol/HDL ratio. The current study concluded that panax ginseng supplement may be useful in improving hyperlipidaemia more than alpha-lipoic acid in newly investigated hypercholesterolemic patients." @default.
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• W2183204080 date "2013-01-01" @default.
• W2183204080 modified "2023-09-23" @default.
• W2183204080 title "Lipid Lowering Effect of Ginseng and Alpha-Lipoicacid in Hypercholesterolemic Patients" @default.
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