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- W2183350970 abstract "Abstract The FGF-related proto-oncogene int-2 is implicated in mouse embryogenesis, since it is expressed in specific tissues during gastrulation and neurulation (Wilkinson et al. 1988). Here, we describe the expression of this gene during subsequent fetal development, int-2 transcripts are restricted to Purkinje cells in the cerebellum and to regions of the developing retina containing early-stage differentiating cells. This high level expression is not detected in the mature cerebellum or retina. In addition, int-2 RNA is detected in the mesenchyme of the developing teeth and in sensory regions of the inner ear. This complex and dynamic pattern suggests multiple roles of this proto-oncogene during fetal development of the mouse." @default.
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- W2183350970 date "1989-01-01" @default.
- W2183350970 modified "2023-10-04" @default.
- W2183350970 title "Expression pattern of the FGF-related proto-oncogene <i>int-2</i> suggests multiple roles in fetal development" @default.
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- W2183350970 doi "https://doi.org/10.1242/dev.105.1.131" @default.
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