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• W2183452034 abstract "CD4+ T lymphocytes from HIV-infected patients with different degrees of disease progression based on CD4 count were expanded in vitro using anti-CD3/28-coated beads.Purified CD4+ T lymphocytes from healthy subjects and patients were expanded for 3 weeks. Moreover, the improvement of cell expansion by IL-2 supplementation was also determined.Expanded CD4+ T lymphocytes from patients had lower fold expansion when compared with healthy subjects. Furthermore, patients with high CD4 counts had higher fold expansion than patients with low CD4 count, and IL-2 supplementation further increased cell expansion.Anti-CD3/28 activation failed to potently induce expansion of CD4+ T lymphocytes from patients. However, the cell expansion could be improved by IL-2 supplementation." @default.
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• W2183452034 date "2015-07-01" @default.
• W2183452034 modified "2023-09-25" @default.
• W2183452034 title "Production of anti-CD3/28 expanded CD4+ T lymphocytes from HIV-infected patients with different degrees of disease progression" @default.
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• W2183452034 doi "https://doi.org/10.2217/imt.15.41" @default.
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