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- W2183563965 abstract "Ischemic stroke is an emergency. Immediate ambulance transp ortation, cautious lowering of excessive blood pressures >220/120mmHg and abstention from heparin and aspirin are the most important measures in the preclinical setting. Hospital prenotification and clearly structured in-hospital pathways can help to reduce delay to treatment. Stroke patients are best treated in dedicated stroke units where vital parameters are monitored and stroke-related complications are recognized. Blood glucose should be in a normal range. Intravenous thrombolysis in the 3 hours window is the only approved efficacious, but time-dependent reperfusion therapy of acute ischemic stroke. Treatment with alteplase >3 to 4.5 hours from symptom onset and in elderly patients >80 years is beneficial and recommended by the European Stroke Organisation, but off-label. In severe stroke with CT-angiographical occlusion of a large intracranial artery, mechanical recanalisation is increasingly used. Only a small proportion of otherwise eligible stroke patients receive reperfusion therapy, mostly due to prehospital delay. The following article highlights on emergency management of acute ischemic stroke, and on strategies how the number of patients who benefit from acute stroke treatment and thrombolytic therapy may be increased." @default.
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- W2183563965 date "2012-09-30" @default.
- W2183563965 modified "2023-09-28" @default.
- W2183563965 title "Management of acute ischemic stroke. The faster, the better" @default.
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