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- W2183565129 abstract "β-carboline are reported to have anticancer activities on cultured cancer cell lines.To further enhance the cytotoxic potency, a series of novel 5-substituted β-carboline derivatives have been synthesized from 5Amino-4-(1H-indol-3-yl)-1,3-dihydro-pyrrol-2-one via Bischler-Napieralski reaction . The newly synthesized compounds were characterized by spectral studies. All compounds were evaluated for in vitro cytotoxic activity against three human cancer cell lines(HeLa,HepG2 and A431 )using MTT assay." @default.
- W2183565129 created "2016-06-24" @default.
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- W2183565129 date "2013-01-01" @default.
- W2183565129 modified "2023-09-26" @default.
- W2183565129 title "Synthesis and in Vitro Cytotoxic Activity of Some Novel β-Carbolines bearing pyrrol-2- one moiety" @default.
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