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- W2183574017 endingPage "763" @default.
- W2183574017 startingPage "745" @default.
- W2183574017 abstract "Infertility cases among men and women of reproductive age have registered a global increase in the last decade. Some infertility cases are idiopathic in nature and may originate from exposures to chemical contaminants in domestic and occupational environmental settings. One group of chemical contaminants that have generated a lot of interest in view of their ubiquitous environmental distribution is polycyclic aromatic hydrocarbons (PAHs), a family of semivolatile and lipophilic compounds that are products of combustion. This chapter focuses on how PAHs impact reproduction and development in animal models and humans using benzo(a)pyrene [B(a)P] as a prototypical PAH toxicant. Topics covered in this chapter include the effect of B(a)P on female reproduction, follicular growth, fetal survival, puberty, reproductive tract function and menopause, male reproduction, and PAH-induced DNA damage in reproductive tissues. The mechanisms that underlie these toxic effects are explained in the context of B(a)P biotransformation and kinetics of B(a)P-reactive metabolite disposition in reproductive tissues. The information presented in this chapter is expected to provoke debate among toxicologists and also raise awareness among caregivers about damage to reproductive health when occupationally exposed individuals dominate the patient populations that frequent infertility clinics." @default.
- W2183574017 created "2016-06-24" @default.
- W2183574017 creator A5026951278 @default.
- W2183574017 creator A5040694140 @default.
- W2183574017 creator A5064385729 @default.
- W2183574017 date "2017-01-01" @default.
- W2183574017 modified "2023-10-01" @default.
- W2183574017 title "Reproductive Toxicity of Polycyclic Aromatic Hydrocarbons" @default.
- W2183574017 cites W1546537221 @default.
- W2183574017 cites W1621380839 @default.
- W2183574017 cites W179283358 @default.
- W2183574017 cites W1964109666 @default.
- W2183574017 cites W1967088423 @default.
- W2183574017 cites W1970222071 @default.
- W2183574017 cites W1970997812 @default.
- W2183574017 cites W1972205705 @default.
- W2183574017 cites W1973368322 @default.
- W2183574017 cites W1974569385 @default.
- W2183574017 cites W1976578540 @default.
- W2183574017 cites W1977754509 @default.
- W2183574017 cites W1978258212 @default.
- W2183574017 cites W1980977242 @default.
- W2183574017 cites W1981379912 @default.
- W2183574017 cites W1982062664 @default.
- W2183574017 cites W1982265633 @default.
- W2183574017 cites W1982525811 @default.
- W2183574017 cites W1985690685 @default.
- W2183574017 cites W1989081094 @default.
- W2183574017 cites W1989682771 @default.
- W2183574017 cites W1990874048 @default.
- W2183574017 cites W1992812212 @default.
- W2183574017 cites W1994141909 @default.
- W2183574017 cites W1994915511 @default.
- W2183574017 cites W1994997247 @default.
- W2183574017 cites W1995944861 @default.
- W2183574017 cites W1998413580 @default.
- W2183574017 cites W1999885398 @default.
- W2183574017 cites W2005029471 @default.
- W2183574017 cites W2005140113 @default.
- W2183574017 cites W2005310807 @default.
- W2183574017 cites W2006231262 @default.
- W2183574017 cites W2006766023 @default.
- W2183574017 cites W2006851675 @default.
- W2183574017 cites W2007158219 @default.
- W2183574017 cites W2008834310 @default.
- W2183574017 cites W2011122698 @default.
- W2183574017 cites W2013340079 @default.
- W2183574017 cites W2013870224 @default.
- W2183574017 cites W2016572372 @default.
- W2183574017 cites W2018466640 @default.
- W2183574017 cites W2024673352 @default.
- W2183574017 cites W2024712394 @default.
- W2183574017 cites W2024814453 @default.
- W2183574017 cites W2025836541 @default.
- W2183574017 cites W2030607204 @default.
- W2183574017 cites W2031302504 @default.
- W2183574017 cites W2031765358 @default.
- W2183574017 cites W2032120945 @default.
- W2183574017 cites W2034072133 @default.
- W2183574017 cites W2035239666 @default.
- W2183574017 cites W2036415863 @default.
- W2183574017 cites W2036514130 @default.
- W2183574017 cites W2038109391 @default.
- W2183574017 cites W2038460887 @default.
- W2183574017 cites W2038764227 @default.
- W2183574017 cites W2040214801 @default.
- W2183574017 cites W2041026780 @default.
- W2183574017 cites W2041482906 @default.
- W2183574017 cites W2042643485 @default.
- W2183574017 cites W2042909270 @default.
- W2183574017 cites W2043108871 @default.
- W2183574017 cites W2044964153 @default.
- W2183574017 cites W2045931107 @default.
- W2183574017 cites W2045940080 @default.
- W2183574017 cites W2046688237 @default.
- W2183574017 cites W2047648892 @default.
- W2183574017 cites W2047939916 @default.
- W2183574017 cites W2050470286 @default.
- W2183574017 cites W2052089730 @default.
- W2183574017 cites W2054683757 @default.
- W2183574017 cites W2058521416 @default.
- W2183574017 cites W2060645387 @default.
- W2183574017 cites W2061312504 @default.
- W2183574017 cites W2065410530 @default.
- W2183574017 cites W2066611091 @default.
- W2183574017 cites W2067256716 @default.
- W2183574017 cites W2067615424 @default.
- W2183574017 cites W2069500150 @default.
- W2183574017 cites W2070066938 @default.
- W2183574017 cites W2070682612 @default.
- W2183574017 cites W2070841856 @default.
- W2183574017 cites W2070960547 @default.
- W2183574017 cites W2071458317 @default.
- W2183574017 cites W2073223435 @default.
- W2183574017 cites W2074305712 @default.
- W2183574017 cites W2077049599 @default.
- W2183574017 cites W2077147263 @default.
- W2183574017 cites W2077945512 @default.