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- W2183600572 abstract "Type 2 diabetes mellitus (T2DM) is associated with platelet hyperreactivity, endothelial dysfunction and an increased risk of cardiovascular complications. Besides, oral antidiabetic agents alter the platelet functions. The aim of this study was to assess the effect of single dose repaglinide, a novel oral antidiabetic, on platelet functions. Thirty-seven newly diagnosed type 2 diabetic patients without any concomitant disease, macrovascular diabetic complications and free of any treatment were enrolled to the study. Oral repaglinide 0.5-2 mg was administered to all participants before each principal meal and platelet aggregation was studied before and one hour after a standardized meal. There was no statistically significant difference in platelet aggregation test results before and after single dose repaglinide administration. Results of our study imply that a single dose of repaglinide has no effect on platelet aggregation in the acute phase of type 2 diabetic patients." @default.
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- W2183600572 date "2010-01-01" @default.
- W2183600572 modified "2023-10-18" @default.
- W2183600572 title "Single Dose Repaglinide Has No Acute Effect On Platelet Aggregation in Newly Diagnosed Type 2 Diabetes Mellitus Patients" @default.
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