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• W2183620497 abstract "of all body parts. He considered the demonstration that the fatty sheaths of peripheral nerve were related to cells particularly compelling support for his cell theory. The question whether the fatty myelin sheath derived from the cell of Schwann during development was debat ed during the ensuing century and finally was settled when the resolution of the electron microscope allowed demon­ stration that the myelin sheath was formed from Schwann cell plasma membrane. The resolution of the electron microscope was also required to demon­ strate the precise nature of ensheathment of unmyelinated nerve fibers (fibers of Remak). Ultrastructural studies established that these nerve fibers are provided with an investment of Schwann cell cytoplasm rather than a thin layer of myelin, as was often stated earlier. This cytoplasmic ensheathment has now been studied in considerable detail, although its functional contribution to the enclosed axon remains enigmatic. We know now that, with rare exceptions, Schwann cells encircle all nerve fibers in peripheral nerve. One Schwann cell either encloses one axon, with a myelin sheath and associated cytoplasm, or a number of unmyelinated axons, each one harbored within a furrow of cytoplasm. These Schwann cell-neurite units are further enveloped by a sleeve of basal lamina, and this" @default.
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• W2183620497 date "1986-01-01" @default.
• W2183620497 modified "2023-09-27" @default.
• W2183620497 title "LINKAGE BETWEEN AXONAL ENSHEATHMENT AND BASAL LAMINA PRODUCTION" @default.
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